ABN192

Anti-ZFP36L1 Antibody

from rabbit, purified by affinity chromatography

• Synonym(s): Zinc finger protein 36, C3H1 type-like 1, Butyrate response factor 1, EGF-response factor 1, ERF-1, Protein TIS11B
• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702

Properties

• Product Name: Anti-ZFP36L1 Antibody, from rabbit, purified by affinity chromatography
• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• purified by: affinity chromatography
• species reactivity: human
• species reactivity (predicted by homology): bovine (based on 100% sequence homology), canine (based on 100% sequence homology), horse (based on 100% sequence homology), mouse (based on 100% sequence homology), rat (based on 100% sequence homology)
• technique(s): western blot: suitable
• NCBI accession no.: NP_001231627
• UniProt accession no.: Q07352
• shipped in: wet ice
• target post-translational modification: unmodified
• Quality Level: 100
• Gene Information: human ... ZFP36L1(677)

Description

Analysis Note

Control
HeLa cell lysate

Evaluated by Western Blot in HeLa cell lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected ZFP36L1 in 10 µg of HeLa cell lysate.

Application

Anti-ZFP36L1 detects levels of ZFP36L1 proteins & has been published & validated for use in WB.

Research Category
Neuroscience

Research Sub Category
Neurodegenerative Diseases

Biochem/physiol Actions

This antibody recognizes the C-terminus of ZFP36L1.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

As a member of the ZFP36/tristetraprolin (TTP) family of zinc finger proteins, ZFP36L1 serves as an RNA-binding protein (RBP) that is known to interact with AU-rich elements in the 3’-untranslated region of mRNAs, resulting in their degradation. It serves as a target for Keratinocyte-derived growth factors and cytokines. ZFP36L1 is reported to play an important role in various physiological processes, including wound healing, epidermal homeostasis, inflammation, erythroid differentiation, thymocyte development, and in the prevention of malignant transformation. Defects in the ZFPP36L1 gene have been implicated in Mutiple Sclerosis and cancer.

~38 kDa observed

Immunogen

Epitope: C-terminus

KLH-conjugated linear peptide corresponding to the C-terminus of Human ZFP36L1.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable