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About This Item
CAS Number:
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
232-619-9
MDL number:
Product Name
Lipase from Candida rugosa, lyophilized, powder (fine), 15-25 U/mg
InChI key
QWZUIMCIEOCSJF-CHHCPSLASA-N
InChI
1S/C11H9N3O2.Na/c15-8-4-5-9(10(16)7-8)13-14-11-3-1-2-6-12-11;/h1-7,16H,(H,12,14);/q;+1/b13-9-;
biological source
fungus (Candida rugosa)
form
lyophilized solid
powder (fine)
quality
lyophilized
specific activity
15-25 U/mg
mol wt
Mr ~67000
storage temp.
2-8°C
Quality Level
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Application
Lipase from Candida rugosa has been used:
- for the resolution of chiral compounds and the transesterification production of biodiesel.
- for studying the immobilization of different lipase enzymes on graphene oxide support for high-efficiency biocatalysis.
Biochem/physiol Actions
Candida rugosa lipase is known to catalyze hydrolysis reactions, especially the production of ricinoleic acid.
Lipases catalyze the hydrolysis of triacylglycerols into glycerol and free fatty acids.
General description
Research area: Cell signaling
Lipase is a part of the alpha/beta-hydrolase fold superfamily of enzymes and is expressed in multiple tissues, including the liver, adipocytes, small intestine, and endothelial surface.
Lipase is a part of the alpha/beta-hydrolase fold superfamily of enzymes and is expressed in multiple tissues, including the liver, adipocytes, small intestine, and endothelial surface.
Other Notes
1 U corresponds to the amount of enzyme which liberates 1 μmol oleic acid per minute at pH 8.0 and 40 °C (triolein, Cat. No. 62314 as substrate)
A highly stereospecific catalyst suitable for preparative resolution of racemic acids and alcohols; Stereoselective ester synthesis; Benzyl-alkyl transesterification under mild neutral conditions; Enantioselectivity of some lipases: Review
signalword
Danger
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Lipase enzymes on graphene oxide support for high-efficiency biocatalysis
Hermanova S, et al.
Applied Materials Today, 5, 200- 208 (2016)
A. Gutman et al.
Tetrahedron, 48, 8775-8775 (1992)
B Cambou et al.
Biotechnology and bioengineering, 26(12), 1449-1454 (1984-12-01)
Lipase from Candida cylindracea has been found to be a highly stereospecific catalyst suitable for preparative resolution of racemic acids and alcohols. Using (R, S)-2-(p-chlorophenoxy) propionic acid (whose R isomer is a herbicide) and (R, S)-sec-butanol (a versatile synthon) as
Y. Ikushima et al.
Chemistry Letters (Jpn), 109-109 (1993)
Biochemistry, Lipase
Pirahanchi Y and Sharma S
StatPearls [Internet] (2023)
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