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Merck

M6020

D-(+)-Mannose

powder, BioReagent, suitable for cell culture

Synonym(s):

D-Mannopyranose

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€140.00

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€491.00

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€1,710.00

€140.00

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About This Item

Empirical Formula (Hill Notation):
C6H12O6
CAS Number:
3458-28-4
Molecular Weight:
180.16
Beilstein:
1564373
EC Number:
222-392-4
MDL number:
MFCD00064122
UNSPSC Code:
12352201
PubChem Substance ID:
24897068
NACRES:
NA.75

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biological source

plant (Spruce, Birch or Beech Wood, Glucose)

Quality Level

300

product line

BioReagent

Assay

≥99%

form

powder

technique(s)

cell culture | mammalian: suitable

mp

133-140 °C (lit.)

solubility

H2O: 50 mg/mL

application(s)

agriculture

SMILES string

OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5+,6?/m1/s1

InChI key

WQZGKKKJIJFFOK-QTVWNMPRSA-N

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1 of 4

This Item
635826357992683
D-(+)-Mannose powder, BioReagent, suitable for cell culture

Sigma-Aldrich

M6020

D-(+)-Mannose

D-(+)-Mannose ≥99.0% (sum of enantiomers, HPLC), suitable for microbiology

Millipore

63582

D-(+)-Mannose

D-(+)-Mannose BioUltra, ≥99.5% (sum of enantiomers, HPLC)

Sigma-Aldrich

63579

D-(+)-Mannose

D-(+)-Mannose analytical standard

Supelco

92683

D-(+)-Mannose

technique(s)

cell culture | mammalian: suitable

technique(s)

-

technique(s)

-

technique(s)

-

assay

≥99%

assay

≥99.0% (sum of enantiomers, HPLC)

assay

≥99.5% (sum of enantiomers, HPLC)

assay

≥95.0% (HPLC)

biological source

plant (Spruce, Birch or Beech Wood, Glucose)

biological source

-

biological source

-

biological source

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

solubility

H2O: 50 mg/mL

solubility

H2O: 0.1 g/mL, clear, colorless

solubility

H2O: 1 M, clear, colorless

solubility

-

form

powder

form

powder

form

solid

form

-

General description

Mannose is an aldohexose carbohydrate. It is isomer of glucose with varying C2 position configuration.[1] Majority of mannose is synthesised from its epimer glucose.[2] It is part of the glycans present in endoplasmic reticulum (ER)/Golgi.[2]

Application

D-(+)-Mannose has been used:
  • as a reference standard in monosaccharide analysis and quantification from sea squirts Ascidiella aspersa[3]
  • as a medium component for the selection of P898012 sorgum seeds transfected with Agrobacterium[4]
  • in segmented filamentous bacterium (SFB) medium supplement for culturing human cell lines[5]

Mannose is an aldohexose carbohydrate. This product may be used to study the effects of exogenous mannose on in vitro processes such as glycosylation.

Biochem/physiol Actions

Mannose may be used to study the effects of exogenous mannose on in vitro processes such as glycosylation. cis-Golgi glycoproteins have high mannose and are prone to Endoglycosidase H or peptide N-glycosidase (N-glycanase) digestion.[6]

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCP1297
BCCN8822
BCCN3304
BCCN3148
BCCN0245

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Metabolic manipulation of glycosylation disorders in humans and animal models
Freeze HH and Sharma V
Seminars in Cell & Developmental Biology, 21(6), 655-662 (2010)
Agrobacterium-mediated transformation of Sorghum bicolor using immature embryos
Transgenic Plants, 109-122 (2012)
Essentials of Carbohydrate Chemistry by John F. Robyt
Pendarvis R
The Chemical Educator, 3(5), 1-2 (1998)
M J Carlino et al.
Gut microbes, 12(1), 1-21 (2020-11-03)
Infectious diarrhea causes approximately 179 million illnesses annually in the US. Multiplex PCR assays for enteric pathogens detect enteropathogenic Escherichia coli (EPEC) in 12-29% of diarrheal stool samples from all age groups in developed nations. The aim of this study
Golgi glycosylation
Stanley P
Cold Spring Harbor Perspectives in Biology, 3(4), a005199-a005199 (2011)
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