N7381

β-Nicotinamide adenine dinucleotide hydrate

Grade AA-1

• Synonym(s): β-DPN, β-NAD, Coenzyme 1, Cozymase, DPN, Diphosphopyridine nucleotide, NAD, Nadide
• Empirical Formula (Hill Notation): C₂₁H₂₇N₇O₁₄P₂ · xH₂O
• CAS Number: 53-84-9
• Molecular Weight: 663.43 (anhydrous basis)
• MDL number: MFCD00036253
• UNSPSC Code: 41106305
• eCl@ss: 39200202
• PubChem Substance ID: 24897823
• NACRES: NA.55

Properties

• biological source: yeast
• Quality Level: 200
• type: Grade AA-1
• form: powder
• IVD: not for in vitro diagnostic use
• color: white to off-white
• storage temp.: −20°C
• SMILES string: NC1=NC=NC2=C1N=CN2.O[C@@H]3[C@@H](COP(O)(OP(OC[C@@H](O4)[C@@H](O)[C@@H](O)[C@H]4[N+]5=CC=CC(C(N)=O)=C5)([O-])=O)=O)OC[C@@H]3O
• InChI: 1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1
• InChI key: BAWFJGJZGIEFAR-NNYOXOHSSA-N

Description

General description

β-Nicotinamide adenine dinucleotide (β-NAD) is a ubiquitous biomolecule containing an adenylic acid and a nicotinamide-5′-ribonucleotide group linked together by a pyrophosphate moiety. In NAD⁺ complexes, the enzyme-cofactor interactions are highly conserved.[1]

Application

β-Nicotinamide adenine dinucleotide hydrate has been used as a supplement in chocolate agar plates for Haemophilus influenzae growth.[2]

Biochem/physiol Actions

β-Nicotinamide adenine dinucleotide (β-NAD) is an electron carrier[3] and a cofactor, significantly involved in enzyme-catalyzed oxido-reduction processes[1] and many genetic processes.[4] NAD cycles between the oxidized (NAD⁺) and reduced (NADH) forms to maintain a redox balance necessary for continued cell growth.[4] NAD is also involved in microbial catabolism.[4] β-NAD acts as a substrate for various enzymes in several cellular processes.[5]

Electron acceptor

Packaging

Packaged by solid weight.

Preparation Note

Produced by fermentation.

Other Notes

This is the common form of NAD.

Safety Information

• Pictograms: GHS08
• Signal Word: Warning
• Hazard Statements: H371
• Precautionary Statements: P260 - P264 - P270 - P308 + P311 - P405 - P501
• Hazard Classifications: STOT SE 2
• Target Organs: Eyes,Central nervous system
• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable