SAB5700391

Anti-Phospho-Jak3-Y980/981 antibody produced in rabbit

• Synonym(s): JAK-3, JAK3, JAK3_HUMAN, JAKL, L-JAK, LJAK
• UNSPSC Code: 12352203
• NACRES: NA.43

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: 121; 125; 68
• species reactivity: mouse, rat, human
• concentration: 1mg/ml
• technique(s): western blot: 1:500-1:2000
• UniProt accession no.: P52333
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pTyr980/pTyr981)
• Gene Information: human ... JAK3(3718)

Description

General description

The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).

Immunogen

A synthetic phosphorylated peptide around Y980 of human Jak3 (NP_000206.2).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Preparation Note

Store at -20℃. Avoid freeze / thaw cycles.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable