AB3000

Anti-IP3 Receptor Type II Antibody

Name: Anti-IP3 Receptor Type II Antibody
Brand: MM

Chemicon^®, from rabbit

Synonyme(s) :

Inositol 1,4,5-Trisphosphate Receptor

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A propos de cet article

Code UNSPSC :

12352203

eCl@ss :

32160702

Nomenclature NACRES :

NA.41

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Source biologique

rabbit

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Produit purifié par

affinity chromatography

Espèces réactives

mouse, hamster, human, monkey, rat

Fabricant/nom de marque

Chemicon^®

Technique(s)

immunocytochemistry: suitable
immunofluorescence: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

Numéro d'accès NCBI

NM_002223.2

Numéro d'accès UniProt

Q14571

Conditions d'expédition

wet ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... ITPR2(3709)

Comparer avec des articles similaires

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1 of 4

Cet article	AB9074	AB9076	HPA040454
Sigma-Aldrich AB3000 Anti-IP3 Receptor Type II Antibody	Sigma-Aldrich AB9074 Anti-IP3 Receptor 2 Antibody	Sigma-Aldrich AB9076 Anticorps anti-récepteur 3 IP3	Sigma-Aldrich HPA040454 Anti-ITPKA antibody produced in rabbit
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
antibody form affinity isolated antibody	antibody form serum	antibody form serum	antibody form affinity isolated antibody
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
clone polyclonal	clone polyclonal	clone polyclonal	clone polyclonal
Gene Information human ... ITPR2(3709)	Gene Information human ... ITPR2(3709)	Gene Information human ... ITPR3(3710) mouse ... Itpr3(16440) rat ... Itpr3(25679)	Gene Information human ... ITPKA(3706)
species reactivity mouse, hamster, human, monkey, rat	species reactivity human, mouse	species reactivity mouse, rat, human	species reactivity human

Immunogène

Synthetic peptide corresponding to the carboxy terminus of the rat Type II receptor

Application

Anti-IP3 Receptor Type II Antibody detects level of IP3 Receptor Type II & has been published & validated for use in IC, IF, IH, IP & WB.

Research Category
Signaling

Research Sub Category
GPCR, cAMP/cGMP & Calcium Signaling

Western blot: 1:50 - 1:100 (detects a 260 kDa band)

Immunofluorescence: 1:10 - 1:20

Immunoprecipitation

Immunocytochemistry: Known to give positive reactivity on AR4-2J, HL-60, COS-I, HEK-293, and RBL-2H3 cell lines.

Immunohistochemistry: Paraformaldehyde or methanol fixes are effective.

Optimal working dilutions must be determined by end user.

Actions biochimiques/physiologiques

Rabbit anti-Type II Inositol 1,4,5-Trisphosphate Receptor (IP3R) is directed against a synthetic peptide corresponding to the carboxy terminus of the rat Type II receptor. The antibody is reactive with Type II IP3R from rat, mouse, human, hamster, and monkey.

Forme physique

Affinity purified versus immobilized immunogen peptide. Liquid in PBS buffer, containing 0.05% BSA, 10% glycerol, 0.005% sodium azide. Caution: Sodium azide is hazardous. MSDS available upon request.

Notes préparatoires

Maintain frozen at -20°C in undiluted aliquots for up to 12 months.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Agonist-evoked inositol trisphosphate receptor (IP3R) clustering is not dependent on changes in the structure of the endoplasmic reticulum.

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The Biochemical journal, 394(Pt 1), 57-66 (2005-11-09)

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Oxsterol binding protein-related protein 4 (ORP4) is essential for cell proliferation, but the underlying mechanism is unclear. ORP4 is expressed as three variants, ORP4L, ORP4M and ORP4S. Here, we reported that silencing of ORP4L with specific small interfering RNA (siRNA)

Identification of KRAP-expressing cells and the functional relevance of KRAP to the subcellular localization of IP3R in the stomach and kidney.

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International journal of molecular medicine, 30(6), 1287-1293 (2012-09-21)

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