FCABS301A4

Milli-Mark^® Anti-dimethyl-Histone H3 (Lys9)-Alexa Fluor^™488 Antibody

Milli-Mark^®, from rabbit

• Synonyme(s) : H3 histone family, member T, histone 3, H3, histone cluster 3, H3
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Conjugué: ALEXA FLUOR^™ 488
• Forme d'anticorps: purified immunoglobulin
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Espèces réactives: human
• Fabricant/nom de marque: Milli-Mark^®
• Technique(s): flow cytometry: suitable
• Isotype: IgG
• Numéro d'accès NCBI: NP_003484
• Numéro d'accès UniProt: Q16695
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: dimethylation (Lys9)
• Informations sur le gène: human ... H3C1(8350)

Description

Description générale

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the ′beads on a string′ structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

15.5 kDa Calculated

Immunogène

Epitope: Methylated at Lys9dimethylated Lys 9 of Human Histone H3

KLH-conjugated, 2X-branched synthetic peptide corresponding to dimethyl-lysine at residue 9 of human Histone H3.

Application

Milli-Mark Anti-dimethyl-Histone H3 (Lys9)-Alexa Fluor488 Antibody detects level of dimethyl-Histone H3 (Lys9)-Alexa Fluor488 & has been published & validated for use in FC.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Histones

Actions biochimiques/physiologiques

Antibody recognizes human Histone H3 dimethylated on lysine 9.

Forme physique

Protein A purified

Purified rabbit polyclonal IgG conjugated to Alexa Fluor 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA

Notes préparatoires

Maintain refrigerated at 2-8°C protected from light for up to 6 months from date of receipt.

Remarque sur l'analyse

Control
HeLa Cells

Evaluated by flow cytometry using HeLa cells

Informations légales

ALEXA FLUOR is a trademark of Life Technologies

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable