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MilliporeSigma

59964

Histamine

analytical standard

Synonyme(s) :

2-(4-Imidazolyl)ethylamine

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100 MG

58,57 $

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A propos de cet article

Formule empirique (notation de Hill) :
C5H9N3
Numéro CAS:
Poids moléculaire :
111.15
Beilstein:
2012
Numéro CE :
Numéro MDL:
Code UNSPSC :
85151701
ID de substance PubChem :
Nomenclature NACRES :
NA.24

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Qualité

analytical standard

Niveau de qualité

Essai

≥97.0% (TLC)
≥97.0% (anhydrous basis, NT)

Durée de conservation

limited shelf life, expiry date on the label

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Impuretés

≤4.0% water

Couleur

white to light yellow

pb

167 °C/0.8 mmHg (lit.)

Pf

83-84 °C (lit.)

Format

neat

Température de stockage

−20°C

Chaîne SMILES 

NCCc1c[nH]cn1

InChI

1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)

Clé InChI

NTYJJOPFIAHURM-UHFFFAOYSA-N

Informations sur le gène

human ... HRH1(3269)

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Cet article
H7125Y000177945321
Histamine analytical standard

Supelco

59964

Histamine

Histamine European Pharmacopoeia (EP) Reference Standard

Y0001779

Histamine

Ametryn PESTANAL®, analytical standard

Supelco

45321

Ametryn

format

neat

format

-

format

neat

format

neat

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

grade

analytical standard

grade

-

grade

pharmaceutical primary standard

grade

analytical standard

assay

≥97.0% (TLC)

assay

≥97.0%

assay

-

assay

-

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

-

shelf life

limited shelf life, expiry date on the label

impurities

≤4.0% water

impurities

-

impurities

-

impurities

-

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Actions biochimiques/physiologiques

Endogenous H1 and H2 histamine receptor agonist; H1 activation mobilizes Ca2+; H2 activation stimulates adenylate cyclase activity in neurons; activates nitric oxide synthetase; potent vasodilator.
Endogenous H1 and H2 histamine receptor agonist; activates nitric oxide synthetase; potent vasodilator.

Pictogrammes

Skull and crossbonesHealth hazard

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Oral - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Certificats d'analyse (COA)

Lot/Batch Number

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

W Tang et al.
Oncogene, 33(20), 2629-2638 (2013-06-12)
Recent studies suggested that cancer stem cells (CSCs) are capable of differentiating into endothelial cells and tumor endothelium may be derived from CSCs. But the mechanism remains unclear. We showed that vascular endothelial growth factor (VEGF) induced the expression of
P J Turner et al.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 25(7), 657-661 (2014-10-10)
Most children with egg allergy tolerate egg in baked foods, such as cake, but tolerance cannot be predicted with conventional allergy testing. We hypothesized that the skin prick test (SPT) wheal to unprocessed raw egg might predict tolerance of baked
Ye Zhang et al.
Investigative ophthalmology & visual science, 56(1), 563-570 (2015-01-13)
We estimate and compare change in iris cross-sectional area (IA) after physiologic and pharmacologic mydriasis in subjects with different dominant mechanisms for primary angle closure. Anterior segment optical coherence tomography (AS-OCT) measurements in light, dark, and following pharmacologic dilation were
Mohamed H Shamji et al.
The Journal of allergy and clinical immunology, 135(4), 913-921 (2014-12-03)
Immunotherapy inhibits basophil histamine release, but the assay is cumbersome, and no one has studied the effects of immunotherapy withdrawal. Intracellular fluorochrome-labeled diamine oxidase (DAO) was used as a novel functional readout of basophil histamine release after immunotherapy. Results were
Katsuya Nagai et al.
Amino acids, 43(1), 97-109 (2012-03-01)
L-carnosine (β-alanyl-L-histidine; CAR) is synthesized in mammalian skeletal muscle. Although the physiological roles of CAR have not yet been clarified, there is evidence that the release of CAR from skeletal muscle during physical exercise affects autonomic neurotransmission and physiological functions.

Questions

1–4 of 4 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  3. How should Product 59964, Histamine analytical standard , be dissolved and what is the solution stability, where the solution should be stored?

    1 answer
    1. No direct solution stability studies have been performed on this product. It is expected that the compound can be reconstituted in water and stored at -20°C. Information with related histamine products indicates solubility at 100 mg/mL in water. Please keep in mind that the solvent used for reconstitution may vary based on the application.

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  4. 59964 histamine for oral consumption and storage temperature

    1 answer
    1. This product is not suitable for oral consumption. Unless otherwise stated, this product is intended for research use only. It is not suitable for any other purpose, which includes, but is not limited to, unauthorized commercial use, in vitro diagnostic use, or therapeutic use in humans or animals.

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