O7885

Okadaic acid potassium salt from Prorocentrum concavum

≥90% (HPLC), powder

• Synonyme(s) : OA
• Formule empirique (notation de Hill) : C₄₄H₆₇KO₁₃
• Numéro CAS: 155751-72-7
• Poids moléculaire : 843.09
• NACRES: NA.77
• PubChem Substance ID: 24898050
• UNSPSC Code: 12352106
• MDL number: MFCD00214356
• Assay: ≥90% (HPLC)
• Form: powder

Propriétés

• biological source: plant (Prorocentrum concavum)
• Quality Segment: 200
• assay: ≥90% (HPLC)
• form: powder
• color: white
• solubility: H₂O: 0.1 mg/mL, DMSO: soluble, ethanol: soluble
• storage temp.: −20°C
• SMILES string: [K+].CC(CC(O)C1OC2CCC3(CCC(C)(O3)\C=C\C(C)C4CC(C)=CC5(O4)OC(C)(CCC5O)CC(C)(O)C([O-])=O)OC2C(O)C1=C)C6CC7(CCCOC7)COC6C
• InChI: 1S/C46H72O13.K/c1-27-20-35(56-46(22-27)36(48)12-15-42(7,59-46)24-43(8,52)40(50)51)28(2)10-14-41(6)17-18-45(58-41)16-11-34-39(57-45)37(49)30(4)38(55-34)33(47)21-29(3)32-23-44(26-54-31(32)5)13-9-19-53-25-44;/h10,14,22,28-29,31-39,47-49,52H,4,9,11-13,15-21,23-26H2,1-3,5-8H3,(H,50,51);/q;+1/p-1/b14-10+;
• InChI key: CWKZDWKRECTBCU-KMZJGFRYSA-M

Description

Biochem/physiol Actions

Dinoflagellate toxin and an ionophore-like polyether derivative of a 38 carbon, fatty acid. Readily enters cells. Inhibitor of type 1 and type 2A protein phosphatases. Does not inhibit tyrosine phosphatases, alkaline phosphatases or acid phosphatase. Known tumor promotor. Used to study various cellular processes including cell cycle, apoptosis, nitric oxide metabolism and calcium signaling.

Okadaic acid is a dinoflagellate toxin and an ionophore-like polyether derivative of a 38 carbon, fatty acid.

Informations sur la sécurité

• Pictogrammes: GHS06
• Mot-clé: Danger
• Codes de danger: H301 + H311 + H331,H315
• Mentions de précaution: P261 - P280 - P301 + P330 + P331 + P310 - P302 + P352 + P312 - P304 + P340 + P311 - P403 + P233
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Skin Irrit. 2
• Classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Que se passe-t-il ?: WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• EPI (équipement de protection individuelle): Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges