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Merck

ITGAV

integrin, alpha V

Synonymes:
CD51, MSK8, VNRA, VTNR
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(3685) Summary: This gene encodes a protein that is a member of the integrin superfamily. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein undergoes post-translational cleavage to yield disulfide-linked heavy and light chains that combine with multiple integrin beta chains to form different integrins. This protein has been shown to heterodimerize with beta 1, beta 3, beta 5, beta 6, and beta 8; the heterodimer of alpha v and beta 3 is the Vitronectin receptor. This protein interacts with several extracellular matrix proteins to mediate cell adhesion and may play a role in cell migration. It is proposed that this protein may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, May 2013]
  • Mouse(16410) integrin alpha V
  • Rat(296456) integrin, alpha V
  • dog(488437) integrin, alpha V
  • naked mole-rat(101717672) integrin, alpha V
  • domestic guinea pig(100728575) integrin, alpha V
  • domestic cat(101085820) integrin, alpha V
  • chicken(396420) integrin, alpha V
  • Zebrafish(100151255) integrin, alpha V
  • Domestic Rabbit(100008956) integrin, alpha V
  • cow(281875) integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
  • sheep(443143) integrin, alpha V
  • Horse(100068706) integrin, alpha V

Custom & Knockdown Gene Products

Small Molecule - Antagonist

Numéro du produit
Description
Espèce(s)
Gly-Arg-Gly-Asp-Ser-Pro-Lys, ≥97% (HPLC),
Espèce(s)
human

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anticorps anti-intégrine αV β3, clone LM609, clone LM609, Chemicon®, from mouse,
Espèces réactives
avian, bovine, canine, chicken, human, monkey, pig, rabbit
Application
flow cytometry
immunofluorescence

immunohistochemistry

immunoprecipitation (IP)
αβ, clone 10D5, Chemicon®, from mouse,
Espèces réactives
human, mouse, rat
Application
flow cytometry
immunoprecipitation (IP)
Anticorps anti-intégrine αVβ5, clone P1F6, clone P1F6, Chemicon®, from mouse,
Espèces réactives
chicken, human
Application
flow cytometry
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)
Anti-Integrin αVβ8 Antibody, clone EM13309 , ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human
Application
flow cytometry
immunocytochemistry

immunohistochemistry

western blot
Anti-Integrin alpha5 (Preservative Free) Antibody, clone SNAKA51, clone SNAKA51, from mouse, purified by using protein G,
Espèces réactives
human
Application
activity assay
immunocytochemistry

western blot

Proteins

Numéro du produit
Description
Espèce(s)
Human Integrin αVβ3 Protein, Triton X-100 Formulation, ,
Espèce(s)
human
Human Integrin αVβ3, Octyl-β-D-glucopyranoside Formulation, ,
Espèce(s)
human

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Itgav,
Espèce(s)
mouse
MISSION® esiRNA, targeting human ITGAV,
Espèce(s)
human