This product is tested for suitability in HPLC. The minimum purity of this material is 97%, and the maximum water content is 2.0 mol. These values are lot-specific and reported in the Certificate of Analysis. This material is not tested for use as an analytical standard. Suitability for this application would have to be determined by the end user. Please see the link below to review a sample or lot specific Certificate:
https://www.sigmaaldrich.com/product/sigma/p1499#product-documentation
P1499
Pterostilbene
≥97% (HPLC), apoptosis inducer, solid
Synonyme(s) :
Pterocarpus marsupium, 3,5-Dimethoxy-4′-hydroxystilbene, 4-[(1E)-2-(3,5-Dimethoxyphenyl)ethenyl]phenol
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| Taille/Référence | Disponibilité | Prix |
|---|---|---|
10 mg | Vérifier la disponibilité des articles du panier | 298.00 CHF |
A propos de cet article
Formule empirique (notation de Hill) :
C16H16O3
Numéro CAS:
Poids moléculaire :
256.30
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
eCl@ss:
32160703
Assay:
≥97% (HPLC)
Form:
solid
Storage condition:
protect from light
Service technique
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Laissez-nous vous aiderNom du produit
Pterostilbene, ≥97% (HPLC), solid
Quality Segment
assay
≥97% (HPLC)
form
solid
storage condition
protect from light
solubility
DMSO: >20 mg/mL, H2O: insoluble
storage temp.
2-8°C
SMILES string
COc1cc(OC)cc(\C=C\c2ccc(O)cc2)c1
InChI
1S/C16H16O3/c1-18-15-9-13(10-16(11-15)19-2)4-3-12-5-7-14(17)8-6-12/h3-11,17H,1-2H3/b4-3+
InChI key
VLEUZFDZJKSGMX-ONEGZZNKSA-N
General description
Application
Pterostilbene has been used:
- to investigate its anti-oxidative stress activities and the involvement of the nuclear factor (erythroid-derived 2)-like 2 (Nrf2)-antioxidant response element (ARE) signaling pathway
- to determine its effects on transcriptional activation of estrogen receptor-α (ERα) in hormone resistant breast cancer cells)
- to study its effects on the cytotoxicity of 2-chloroethyl ethyl sulphide (CEES) in human epidermoid carcinoma cells (A-431) through MTT (3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide)viability assay
Biochem/physiol Actions
Pterostilbene exhibits antineoplastic properties in some of the malignancies, hence it is considered as an active anticancer agent. It has the ability to stimulate apoptosis and block the viability of cell in estrogen-receptor positive and negative breast cancer cell lines.
Antioxidant, antiproliferative, apoptosis inducer, antihyperglycemic, antidiabetic.
Disclaimer
Air-sensitive
1 of 1
Cet article | |||
|---|---|---|---|
| description ≥97% (HPLC), solid | description - | description phyproof® Reference Substance | description - |
| assay ≥97% (HPLC) | assay - | assay ≥98.0% (HPLC) | assay - |
| form solid | form - | form - | form - |
| Quality Level 100 | Quality Level - | Quality Level - | Quality Level - |
| storage temp. 2-8°C | storage temp. - | storage temp. 2-8°C | storage temp. - |
| storage condition protect from light | storage condition - | storage condition - | storage condition - |
| solubility H2O: insoluble, DMSO: >20 mg/mL | solubility - | solubility - | solubility - |
Mot-clé
Danger
Codes de danger
Mentions de précaution
Hazard Classifications
Aquatic Chronic 2 - Eye Dam. 1
Classe de stockage
11 - Combustible Solids
WGK
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
EPI (équipement de protection individuelle)
dust mask type N95 (US), Eyeshields, Gloves
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Actually we are using as a Analytical Standard for HPLC assay of Pterostilbene in RM and Final Product .Can we use this? if we can use How much purity we have to take for Calculation
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