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700147P

Avanti

PhotoClick Cholesterol

Avanti Research™ - A Croda Brand

Synonyma:

hex-5-yn-1-yl 4-((3S,5S)-3-hydroxy-10, 13-dimethyl-1,2,3,4,5,7,8,9,10,11,12,13,14,15,16,17-hexadecahydrospiro[cyclopenta[a]phenanthrene-6,3′-diazirin]-17-yl)pentanoate

Přihlásit pro zobrazení organizačních a smluvních cen.

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Vám/Skladová položkaDostupnostCena
100 μg
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6 440,00 Kč
250 μg
Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti.
13 800,00 Kč

O této položce

Empirický vzorec (Hillův zápis):
C30H46N2O3
Číslo CAS:
1485490-47-8
Molekulová hmotnost:
482.70
MDL number:
MFCD00870345
NACRES:
NA.25
UNSPSC Code:
12352211

6 440,00 Kč

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Název produktu

PhotoClick Cholesterol, Hex-5′-ynyl 3β-hydroxy-6-diazirinyl-5α-cholan-24-oate, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 100 μg (with stopper and crimp cap (700147P-100ug)), pkg of 1 × 250 μg (with stopper and crimp cap (700147P-250ug))

manufacturer/tradename

Avanti Research™ - A Croda Brand 700147P

lipid type

click reagents

shipped in

dry ice

storage temp.

−20°C

General description

PhotoClick Cholesterol is a clickable, photoreactive sterol probe for use in combination with quantitative mass spectrometry to globally map cholesterol-protein interactions directly in living cells. In addition to the UV-activatable cross-linking diazirine group that reacts with proteins, the sterol contains an alkyne group for incorporation of reporter and affinity tags through click-chemistry.
PhotoClick Cholesterol is a synthetic analog of cholesterol and is photoreactive. It comprises the alkyne group.[1]

Application

PhotoClick Cholesterol has been used:
  • in lysosome-associated membrane protein 1 (LAMP1) crosslinking studies[2]
  • as an analog of cholesterol in binding and competition assay of sterol binding proteins from yeast[1]
  • as a conjugate with the ectodomain of lysosomal integral membrane protein-2 (LIMP-2)[3]

Biochem/physiol Actions

PhotoClick Cholesterol serves as a probe for tracking cholesterol-binding proteins. The copper-catalyzed azide-alkyne cycloaddition is the basis for its probe functionality.[4] The alkyne group is essential for the click chemistry property. Its binding to partners is mediated by photocrosslinking.[1]

Packaging

2 mL Amber Serum Vial with Stopper and Crimp Cap (700147P-100ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (700147P-250ug)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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Tato položka
900601P700143P700100P
PhotoClick Cholesterol Hex-5′-ynyl 3β-hydroxy-6-diazirinyl-5α-cholan-24-oate, powder

Avanti

700147P

PhotoClick Cholesterol

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Avanti

900601P

Photoclick sphingosine-1-phosphate

27-alkyne cholesterol Avanti Research™ - A Croda Brand 700143P, powder

Avanti

700143P

27-alkyne cholesterol

Cholesterol (plant) Avanti Research™ - A Croda Brand

Avanti

700100P

Cholesterol (plant)

assay

>99% (TLC)

assay

>99% (TLC)

assay

>99% (TLC)

assay

>99% (TLC)

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

manufacturer/tradename

Avanti Research™ - A Croda Brand 700147P

manufacturer/tradename

Avanti Research™ - A Croda Brand

manufacturer/tradename

Avanti Research™ - A Croda Brand 700143P

manufacturer/tradename

Avanti Research™ - A Croda Brand

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

packaging

pkg of 1 × 100 μg (with stopper and crimp cap (700147P-100ug)), pkg of 1 × 250 μg (with stopper and crimp cap (700147P-250ug))

packaging

pkg of 1 × 250 μg

packaging

pkg of 1 × 100 μg (700143P-100ug)

packaging

pkg of 1 × 1 g (700100P-1g), pkg of 1 × 100 mg (700100P-100mg), pkg of 1 × 200 mg (700100P-200mg), pkg of 1 × 500 mg (700100P-500mg)

form

powder

form

powder

form

powder

form

powder

Skladovací třída

11 - Combustible Solids

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Osvědčení o analýze (COA)

Lot/Batch Number

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