8.18710

Urea

for synthesis

• Synonyma: Carbamide, Carbonyl diamide, Diaminomethanone, Carbonyldiamine, Carbamide, Carbonyldiamide
• Lineární vzorec: NH₂CONH₂
• Číslo CAS: 57-13-6
• Molekulová hmotnost: 60.06
• UNSPSC Code: 12352111
• NACRES: NA.22
• EC Index Number: 200-315-5
• MDL number: MFCD00008022
• Beilstein/REAXYS Number: 635724
• eCl@ss: 32150917

Vlastnosti

• vapor pressure: <0.1 hPa ( 20 °C)
• Quality Segment: 200
• potency: 8471 mg/kg LD₅₀, oral (Rat), 8200 mg/kg LD₅₀, skin (Rat)
• pH: 9 (20 °C, 100 g/L in H₂O)
• mp: 132-135 °C (lit.)
• solubility: 1000 g/L
• density: 1.335 g/mL at 25 °C (lit.)
• bulk density: 720‑760 kg/m³
• storage temp.: 2-30°C
• SMILES string: NC(N)=O
• InChI: 1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)
• InChI key: XSQUKJJJFZCRTK-UHFFFAOYSA-N

Popis

Application

Used for the denaturation of proteins and as a mild solubilization agent for insoluble or denatured proteins. Useful for renaturing proteins from samples already denatured with 6 M guanidine chloride such as inclusion bodies. May be used with guanidine hydrochloride and dithiothreitrol (DTT) in the refolding of denatured proteins into their native or active form.

Analysis Note

Assay (ex N): ≥ 99.0 %
Melting range (lower value): ≥ 132 °C
Melting range (upper value): ≤ 135 °C
Identity (IR): passes test

Bezpečnostní informace

• Skladovací třída: 11 - Combustible Solids
• WGK: WGK 1
• Bod vzplanutí (°F): Not applicable
• Bod vzplanutí (°C): Not applicable