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B2929

B-Lymphocyte Chemoattractant human

Name: B-Lymphocyte Chemoattractant human
Brand: SIGMA

≥95% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

Synonyma:

B-Cell Attracting Chemokine 1, BCA-1, BLC

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O této položce

UNSPSC Code:

12352202

NACRES:

NA.32

MDL number:

MFCD01867020

Biological source:

human

Recombinant:

expressed in E. coli

Assay:

≥95% (SDS-PAGE)

Form:

lyophilized powder

Mol wt:

apparent mol wt 8.7 kDa by SDS-PAGE (reducing)

Impurities:

endotoxin, tested

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Vlastnosti

biological source

human

Quality Segment

200

recombinant

expressed in E. coli

assay

≥95% (SDS-PAGE)

form

lyophilized powder

potency

0.1000 μg/mL

mol wt

apparent mol wt 8.7 kDa by SDS-PAGE (reducing)

packaging

pkg of 25 μg

storage condition

avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

UniProt accession no.

O43927

storage temp.

−20°C

Gene Information

human ... CXCL13(10563)

Popis

Biochem/physiol Actions

BCA-1 is a potent chemoattractant for B lymphocytes, but not T lymphocytes, monocytes, or neutrophils.

BCA-1 is a potent chemoattractant for B lymphocytes, but not T lymphocytes, monocytes, or neutrophils. Its specific receptor BLR1 is a G protein-coupled receptor originally isolated from Burkitt′s lymphoma cells. Among cells of the hematopoietic lineages, the expression of BRL1, now designated CXCR5, is restricted to B lymphocytes and a subpopulation of T helper memory cells.

Potent chemoattractant for B lymphocytes, but not T lymphocytes, monocytes, or neutrophils.

The biological activity of human BLC/BCA-1 is measured by its ability to chemoattract mouse BaF/3 cells transfected with human CXCR5.

Physical form

Lyophilized from a 0.2 μm filtered solution in 35% acetonitrile and 0.1% TFA containing 50 μg bovine serum albumin per 1 μg of cytokine.

pictograms

GHS07

signalword

Warning

hcodes

H302 + H332,H319

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2

Skladovací třída

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c