G7403

Glycine

≥99% (titration), suitable for electron microscopy, BioXtra

• Synonyma: Aminoacetic acid, Aminoethanoic acid, Glycocoll
• Lineární vzorec: NH₂CH₂COOH
• Číslo CAS: 56-40-6
• Molekulová hmotnost: 75.07
• NACRES: NA.26
• PubChem Substance ID: 24895306
• eCl@ss: 32160406
• UNSPSC Code: 12352209
• EC Number: 200-272-2
• MDL number: MFCD00008131
• Beilstein/REAXYS Number: 635782

Vlastnosti

• Název produktu: Glycine, BioXtra, ≥99% (titration)
• product line: BioXtra
• Quality Segment: 200
• assay: ≥99% (titration)
• form: powder
• technique(s): electron microscopy: suitable
• impurities: Insoluble matter, passes filter test
• ign. residue: ≤0.05%
• loss: ≤0.05% loss on drying, HV, 20-26 °C
• color: white
• pKa (25 °C): (1) 2.35, (2) 9.60, 2.35
• mp: 240 °C (dec.) (lit.)
• solubility: 1 M HCl: 1 M, clear, colorless
• anion traces: chloride (Cl^-): ≤0.005%, sulfate (SO₄^2-): ≤0.005%
• cation traces: Al: ≤0.0005%, As: ≤0.00001%, Ba: ≤0.0005%, Bi: ≤0.0005%, Ca: ≤0.001%, Cd: ≤0.0005%, Co: ≤0.0005%, Cr: ≤0.0005%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.005%, Li: ≤0.0005%, Mg: ≤0.0005%, Mn: ≤0.0005%, Mo: ≤0.0005%, NH₄⁺: ≤0.02%, Na: ≤0.02%, Ni: ≤0.0005%, Pb: ≤0.0005%, Sr: ≤0.0005%, Zn: ≤0.0005%
• absorption: ≤0.04 at 260 in 1 M HCl at 1 M, ≤0.04 at 280 in 1 M HCl at 1 M
• SMILES string: NCC(O)=O
• UV absorption: λ: 260 nm A_max: ≤0.04, λ: 260 nm A_max: 0.003, λ: 260 nm A_max: 0.006
• InChI: 1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
• InChI key: DHMQDGOQFOQNFH-UHFFFAOYSA-N
• Gene Information: rat ... Grin2a(24409)

Popis

Application

Glycine has been used to quench unreacted aldehyde during sample (nuclei) preparation for scanning electron microscope. It has also been used for sample fixation in the process of immunolabeling.

Biochem/physiol Actions

Glycine is a non-essential amino acid. Influx of calcium through the cell membrane is mediated by glycine-gated channel. Glycine participates in the synthesis of porphyrins, purine and serine. It also serves as a competitive agonist for glutamate in binding to the NMDA (N-methyl-D-aspartate) receptors. Glycine synthesis might be increased in rapidly proliferating cancer cells, due to increased demand for the amino acid.

Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

Bezpečnostní informace

• Skladovací třída: 11 - Combustible Solids
• Co se děje?: WGK 1
• Bod vzplanutí (°F): Not applicable
• Bod vzplanutí (°C): Not applicable
• PPE (osobní ochranné prostředky): Eyeshields, Gloves, type N95 (US)