H1635

N-Hippuryl-His-Leu hydrate

chromogenic, ≥98% (HPLC), powder

• Synonyma: N-Benzoyl-Gly-His-Leu, N-Hippuryl-L-histidyl-L-leucine hydrate
• Empirický vzorec (Hillův zápis): C₂₁H₂₇N₅O₅ · xH₂O
• Číslo CAS: 207386-83-2
• Molekulová hmotnost: 429.47 (anhydrous basis)
• NACRES: NA.32
• PubChem Substance ID: 24895469
• UNSPSC Code: 12352204
• EC Number: 250-597-9
• MDL number: MFCD00149318
• Beilstein/REAXYS Number: 5664178

Vlastnosti

• Název produktu: N-Hippuryl-His-Leu hydrate, powder, ≥98% (HPLC)
• Quality Segment: 200
• assay: ≥98% (HPLC)
• form: powder
• color: white to off-white
• solubility: acetic acid: ~50 mg/mL
• storage temp.: −20°C
• SMILES string: O.CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CNC(=O)c2ccccc2)C(O)=O
• InChI: 1S/C21H27N5O5.H2O/c1-13(2)8-17(21(30)31)26-20(29)16(9-15-10-22-12-24-15)25-18(27)11-23-19(28)14-6-4-3-5-7-14;/h3-7,10,12-13,16-17H,8-9,11H2,1-2H3,(H,22,24)(H,23,28)(H,25,27)(H,26,29)(H,30,31);1H2/t16-,17-;/m0./s1
• InChI key: NWOJMNXIJBZMPK-QJHJCNPRSA-N
• Gene Information: human ... ACE(1636), ACE2(59272) ; mouse ... ACE3(217246) ; rat ... ACE(11421), ACE2(70008), ACE3(498012)

Popis

General description

Substrate for angiotensin converting enzyme.

Application

N-Hippuryl-His-Leu hydrate has been used in the measurement of angiotensin-converting enzyme (ACE) inhibitory activity using oyster hydrolysates, semimembranosus muscle samples, and rabbit lung acetone powder.

Biochem/physiol Actions

N-Hippuryl-His-Leu hydrate (HHL) can be used as an artificial substrate for angiotensin-converting enzyme (ACE).

Bezpečnostní informace

• Skladovací třída: 11 - Combustible Solids
• Co se děje?: WGK 3
• Bod vzplanutí (°F): Not applicable
• Bod vzplanutí (°C): Not applicable
• PPE (osobní ochranné prostředky): Eyeshields, Gloves, type N95 (US)