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H2779

HistoChoice® Clearing Agent

alternative to toluene and xylene

Funkce v oblasti udržitelnosti

Synonyma:

dewaxing mixture for paraffin tissue sections

Přihlásit pro zobrazení organizačních a smluvních cen.

Vybrat velikost

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Vám/SKUDostupnostCena
1 L
Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti.
2 950,00 Kč

O této položce

NACRES:
NA.47
UNSPSC Code:
12171500

2 950,00 Kč


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Quality Segment

form

liquid

sustainability

Sustainability features

color

colorless

density

0.760-0.820 g/mL

application(s)

hematology
histology
tissue diagnostics

greener alternative category

storage temp.

room temp

General description

HistoChoice® is a patented, complex mixture of agents that allow tissues to retain their structure, antigenic sites, and nucleic acid sites. It is a non-toxic, non-cross-linking fixative formulated to replace formaldehyde-based fixation. This formulation in non-citrus, contains no mercury, formaldehyde, or glutaraldehyde.

This product aligns with one or more of the 12 Principles of Green ChemistryThis product has Inherently Safer Chemistry, compared to the standard use of formalin for tissue processing.

Application

HistoChoice® Clearing Agent has the following applications:
  • It is suitable as an alternative to toluene and xylene for dewaxing paraffin tissue sections. Prepared slides are suitable for antibody probing applications and in situ hybridizations.
  • It has been employed in a study to explain the recalcitrance of lignocellulosic plant cell walls to enzymatic degradation.
  • It has been used to develop a novel method to improve sensitivity for the localization of miRNA and their target transcripts in plants.
  • It has been used to study the correlation of cytoplasmic ADP-ribosylation levels with markers of patient outcome in human cancers.

Biochem/physiol Actions

Fixation with HistoChoice® works well in immunohistology applications where its non-cross-linking traits are conducive to epitope retrieval and identification by primary antibodies to extracellular matrix components.

Features and Benefits

  • Non-toxic, non-carcinogenic, and odorless.
  • Non-flammable.
  • Preserves native antigenic and nucleic acid sites.
  • Compatible with many organic mounting media.
  • Dissolves wax faster and evaporates slower than xylene.
  • Can be used in automated processors.
  • Tissues retain their original structure.

Legal Information

HistoChoice is a registered trademark of Amresco, Inc.

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Tato položka
Q2259HISTO1534056
Xylenes histological grade

Sigma-Aldrich

534056

Xylenes

description

alternative to toluene and xylene

description

-

description

-

description

histological grade

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

color

colorless

color

-

color

-

color

-

greener alternative category

greener alternative category

-

greener alternative category

-

greener alternative category

-

Quality Level

100

Quality Level

200

Quality Level

-

Quality Level

100

application(s)

hematology
histology
tissue diagnostics

application(s)

-

application(s)

-

application(s)

histology

sustainability

Sustainability features

sustainability

-

sustainability

-

sustainability

-


Piktogramy

Health hazard

Výstražné slovo

Danger

Kódy nebezpečí

Hazard Classifications

Asp. Tox. 1

Skladovací třída

10 - Combustible liquids

Bod vzplanutí (°F)

141.8 °F

Bod vzplanutí (°C)

61 °C

PPE (osobní ochranné prostředky)

Eyeshields, Gloves, type ABEK (EN14387) respirator filter



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Questions

1–4 of 4 Questions  
  1. What is the pH of HistoChoice® Clearing Agent?

    1 answer
    1. The pH of this product is not determined.

      Helpful?

  2. Hi, I'm curious about the chemical components present in the HistoChoice xylene alternative. In section 3 of the SDS, it states that the component is solely HistoChoice™ Choice Clearing Agent. What exactly is that? Is it limonene-based like HistoClear?

    1 answer
    1. HistoChoice is product of Amresco, Inc. The exact chemical composition is being withheld as proprietary by the supplier. The Safety Data Sheet does provide a list for some hazards to be aware of. The product does not contain benzenoid ring compounds, formaldehyde, glutaraldehyde, or mercury.

      Helpful?

  3. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

  4. Is HistoChoice Clearing Agent, product H2779, compatible with polycarbonate?

    1 answer
    1. The supplier of HistoChoice Clearing Agent has reported no incompatibilities were observed when polycarbonate was exposed to HistoChoice Clearning Agent for at least 1 hour.

      Helpful?

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