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L1012

Linoleic acid

liquid, BioReagent, suitable for cell culture

Synonyma:

cis-9,cis-12-Octadecadienoic acid

Přihlásit pro zobrazení organizačních a smluvních cen.

Vybrat velikost

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Vám/SKUDostupnostCena
100 mg
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1 190,00 Kč
1 g
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1 450,00 Kč
5 g
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4 910,00 Kč

O této položce

Lineární vzorec:
CH3(CH2)4CH=CHCH2CH=CH(CH2)7CO2H
Číslo CAS:
Molekulová hmotnost:
280.45
NACRES:
NA.75
PubChem Substance ID:
eCl@ss:
32190102
UNSPSC Code:
12352211
EC Number:
200-470-9
MDL number:
Beilstein/REAXYS Number:
1727101

1 190,00 Kč


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biological source

plant (Safflower oil)

Quality Segment

product line

BioReagent

assay

≥98%

form

liquid

technique(s)

cell culture | mammalian: suitable

refractive index

n20/D 1.466 (lit.)

bp

229-230 °C/16 mmHg (lit.)

mp

−5 °C (lit.)

solubility

NaOH: 1 M, ethanol: soluble

density

0.902 g/mL at 25 °C (lit.)

storage temp.

−20°C

SMILES string

OC(CCCCCCC/C=C\C/C=C\CCCCC)=O

InChI

1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20)/b7-6-,10-9-

InChI key

OYHQOLUKZRVURQ-HZJYTTRNSA-N

Gene Information

General description

Linoleic acid (LA) is the precursor for the synthesis of arachidonic prostaglandins and other eicosanoids. LA is present in vegetable oils and meat.

Application

Fatty acid that is typically bound to a carrier molecule such as BSA or cyclodextrin for use in cell culture.
Linoleic acid has been used as a component of S12 medium for cardiomyocytes differentiation, minimum essential medium α for spermatogonial stem cell culture and for endothelial differentiation of mouse adipose-derived stem cells (mASC).

Biochem/physiol Actions

Linoleic acid increases cell proliferation and gene expression of PPARα and its target genes such as acyl-CoA oxidase in primary duck hepatocytes .
Linoleic acid (LA) may improve wound healing in diabetic rat. The levels of LA in adipose tissue and platelets are correlated with coronary artery disease. It may induce tumor and apoptosis in colorectal cancer cells. Studies also support their protective effects in lymphocytes. Linoleic acid is typically bound to a carrier molecule such as bovine serum albumin (BSA) or cyclodextrin for use in cell culture.

Packaging

Sealed ampule.

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Tato položka
62230W338020W800075
Linoleic acid analytical standard

Supelco

62230

Linoleic acid

description

liquid, BioReagent, suitable for cell culture

description

analytical standard

description

≥95%, FG

description

natural (US), ≥95%, FG

assay

≥98%

assay

≥98.0% (GC)

assay

≥95%

assay

≥95%

technique(s)

cell culture | mammalian: suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

biological source

plant (Safflower oil)

biological source

-

biological source

synthetic

biological source

(Sunflower seed)

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

form

liquid

form

-

form

-

form

-

solubility

NaOH: 1 M, ethanol: soluble

solubility

-

solubility

-

solubility

-


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Skladovací třída

10 - Combustible liquids

Co se děje?

WGK 1

Bod vzplanutí (°F)

Not applicable

Bod vzplanutí (°C)

Not applicable

PPE (osobní ochranné prostředky)

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)



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Osvědčení o analýze (COA)

Lot/Batch Number

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Questions

1–3 of 3 Questions  
  1. Can I resuspend in DMSO? If so, what is the recommended concentration to resuspend at?

    1 answer
    1. The solubility of this material in DMSO is not determined. However, sources state that Linoleic acid (CAS 60-33-3) is soluble in DMSO at concentrations of at least 43 to 90 mg/mL (approx. 154 to 321 mM). Please note that this information has not been validated internally.

      Helpful?

  2. What volume does the 100mg come dissolved in, i.e., what is the initial concentration? I have 50uL of liquid left, how can I figure out how many mg that is?

    1 answer
    1. Linoleic Acid is provided as a neat, pure liquid. The initial volume can be calculated by dividing the mass by the density. For example, a 100 mg bottle will contain 0.1g divided by 0.902 g/mL, which equals 110 µL.

      Helpful?

  3. What is the concentration (g/L) of the solution

    1 answer
    1. This product is a neat or pure liquid and has not been diluted. The material has a density of 0.902 g/mL and a minimum purity of 99%.

      Helpful?

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