RDD001

Guanidine hydrochloride

anhydrous, free-flowing, Redi-Dri^™, ≥99%

• Synonyma: Aminoformamidine hydrochloride, Aminomethanamidine hydrochloride, Guanidinium chloride
• Lineární vzorec: NH₂C(=NH)NH₂ · HCl
• Číslo CAS: 50-01-1
• Molekulová hmotnost: 95.53
• NACRES: NA.28
• UNSPSC Code: 12352107
• PubChem Substance ID: 329824214
• EC Number: 200-002-3
• Beilstein/REAXYS Number: 3591990
• MDL number: MFCD00013026

Vlastnosti

• grade: anhydrous
• Quality Segment: 100
• product line: Redi-Dri^™
• assay: ≥99%
• quality: free-flowing
• pH: (25 °C, 4.6 - 6/573 g/L)
• mp: 180-185 °C (lit.)
• solubility: H₂O: 6 M
• density: 1.3 g/cm³ (lit.)
• absorption: ≤0.10 at 260 nm in H₂O at 6 M
• SMILES string: Cl[H].NC(N)=N
• InChI: 1S/CH5N3.ClH/c2-1(3)4;/h(H5,2,3,4);1H
• InChI key: PJJJBBJSCAKJQF-UHFFFAOYSA-N
• Gene Information: human ... KCNA1(3736), KCNA10(3744), KCNA2(3737), KCNA3(3738), KCNA4(3739), KCNA5(3741), KCNA6(3742), KCNA7(3743), KCNB1(3745), KCNB2(9312), KCNC1(3746), KCNC2(3747), KCNC3(3748), KCNC4(3749), KCND1(3750), KCND2(3751), KCND3(3752), KCNF1(3754), KCNG1(3755), KCNG2(26251), KCNG3(170850), KCNG4(93107), KCNH1(3756), KCNH2(3757), KCNH3(23416), KCNH4(23415), KCNH5(27133), KCNH6(81033), KCNH7(90134), KCNH8(131096), KCNQ1(3784), KCNQ2(3785), KCNQ3(3786), KCNQ4(9132), KCNQ5(56479), KCNS1(3787), KCNS2(3788), KCNS3(3790), KCNV1(27012), KCNV2(169522)

Popis

Application

Strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary.

Legal Information

Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

Bezpečnostní informace

• Piktogramy: GHS07
• Výstražné slovo: Warning
• Kódy nebezpečí: H302 + H332,H315,H319
• Bezpečnostní pokyny: P261 - P264 - P301 + P312 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
• Skladovací třída: 11 - Combustible Solids
• WGK: WGK 1
• Bod vzplanutí (°F): Not applicable
• Bod vzplanutí (°C): Not applicable