SML1145

ML303

≥98% (HPLC)

• Synonyma: 2-Methoxy-4-(3-methyl-1-(4-(trifluoromethyl)phenyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)phenol
• Empirický vzorec (Hillův zápis): C₂₁H₁₆F₃N₃O₂
• Číslo CAS: 1638211-04-7
• Molekulová hmotnost: 399.37
• UNSPSC Code: 12352202
• PubChem Substance ID: 329825679
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Vlastnosti

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 20 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: CC1=NN(C2=CC=C(C(F)(F)F)C=C2)C3=NC=CC(C4=CC=C(O)C(OC)=C4)=C31
• InChI: 1S/C21H16F3N3O2/c1-12-19-16(13-3-8-17(28)18(11-13)29-2)9-10-25-20(19)27(26-12)15-6-4-14(5-7-15)21(22,23)24/h3-11,28H,1-2H3
• InChI key: YBRHGNCGFMRGSV-UHFFFAOYSA-N

Popis

Biochem/physiol Actions

ML303 is a potent inhibitor (IC₅₀ = 155 nM) of the influenza viral protien NS1. NS1 enhances virulence by inhibiting host cell immune responses, including the expression of IFN-b, and regulating synthesis, splicing and translation of viral RNA.

ML303 is a potent inhibitor of the influenza viral protien NS1.

It belongs to the pyrazolopyridine family.

Bezpečnostní informace

• Piktogramy: GHS06
• Výstražné slovo: Danger
• Kódy nebezpečí: H301
• Bezpečnostní pokyny: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral
• Skladovací třída: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Co se děje?: WGK 3
• Bod vzplanutí (°F): Not applicable
• Bod vzplanutí (°C): Not applicable