1068004

Betamethasone sodium phosphate

United States Pharmacopeia (USP) Reference Standard

• Synonyma: Betamethasone 21-phosphate disodium
• Empirický vzorec (Hillův zápis): C₂₂H₂₈FNa₂O₈P
• Číslo CAS: 151-73-5
• Molekulová hmotnost: 516.40
• NACRES: NA.24
• PubChem Substance ID: 329749107
• UNSPSC Code: 41116107
• MDL number: MFCD00200361
• eCl@ss: 25140904

Vlastnosti

• grade: pharmaceutical primary standard
• agency: USP
• API family: betamethasone
• manufacturer/tradename: USP
• application(s): pharmaceutical; pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: [Na+].[Na+].[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@H](C)[C@]4(O)C(=O)COP([O-])([O-])=O
• InChI: 1S/C22H30FO8P.2Na/c1-12-8-16-15-5-4-13-9-14(24)6-7-19(13,2)21(15,23)17(25)10-20(16,3)22(12,27)18(26)11-31-32(28,29)30;;/h6-7,9,12,15-17,25,27H,4-5,8,10-11H2,1-3H3,(H2,28,29,30);;/q;2*+1/p-2/t12-,15-,16-,17-,19-,20-,21-,22-;;/m0../s1
• InChI key: PLCQGRYPOISRTQ-LWCNAHDDSA-L
• Gene Information: human ... NR3C1(2908)

Popis

General description

Find answers to frequently asked questions on USP products in USP FAQs.

Betamethasone is a corticosteroid with anti-inflammatory and immunosuppressive abilities, used especially where water retention is undesirable. It is applied as a topical cream, ointment, lotion or gel to treat itching (e.g. from eczema). Corticosteroid used to stimulate fetal lung maturation and to decrease the incidence and mortality from intracranial hemorrhage in premature infants

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Betamethasone sodium phosphate Related Compound reference standard suitable for use in specified USP compendial quality tests and assays.

Also used to prepare standard and system suitability solution during the assay and identification by using liquid chromatography in conjunction with UV detector according to the given below monographs of United States Pharmacopeia (USP):

• Dexamethasone Sodium Phosphate
• Betamethasone Sodium Phosphate and Betamethasone Acetate Injectable Suspension
• Betamethasone Sodium Phosphate
• Betamethasone Sodium Phosphate Injection

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Bezpečnostní informace

• Piktogramy: GHS08,GHS07
• Výstražné slovo: Danger
• Kódy nebezpečí: H302,H360FD,H373
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 1B - STOT RE 2
• Cílové orgány: Liver,Kidney,Endocrine system
• Skladovací třída: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Bod vzplanutí (°F): Not applicable
• Bod vzplanutí (°C): Not applicable
• Bezpečnostní pokyny: P202 - P260 - P264 - P280 - P301 + P312 - P308 + P313