156361
Hydantoin
98%
Synonym(s):
2,4-Imidazolidinedione, Glycolylurea
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100 G
CZK 795.00
500 G
CZK 2,445.00
CZK 795.00
List PriceCZK 1,060.00Save 25%Please contact Customer Service for Availability
About This Item
Empirical Formula (Hill Notation):
C3H4N2O2
CAS Number:
Molecular Weight:
100.08
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
207-313-3
Beilstein/REAXYS Number:
110598
MDL number:
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Product Name
Hydantoin, 98%
InChI key
WJRBRSLFGCUECM-UHFFFAOYSA-N
InChI
1S/C3H4N2O2/c6-2-1-4-3(7)5-2/h1H2,(H2,4,5,6,7)
SMILES string
O=C1CNC(=O)N1
assay
98%
form
powder
mp
218-220 °C (lit.)
Quality Level
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Related Categories
1 of 4
This Item | 533653 | 454273 | 34010 |
|---|---|---|---|
| assay 98% | assay 97% | assay 97% | assay - |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| mp 218-220 °C (lit.) | mp 148-152 °C (lit.) | mp 144-150 °C (lit.) | mp - |
| form powder | form - | form - | form - |
Application
Reactant for synthesis of:
N-benzyl aplysinopsin analogs as anticancer agents[1]
D-glutamic acid based inhibitors[2]
Antidiabetic chromonyl-2,4-thiazolidinediones[3]
GSK-3β inhibitors with brain permeability[4]
Thiazolidinedione derivatives as 15-PGDH inhibitors[5]
Radio-sensitizing agents[6]
N-benzyl aplysinopsin analogs as anticancer agents[1]
D-glutamic acid based inhibitors[2]
Antidiabetic chromonyl-2,4-thiazolidinediones[3]
GSK-3β inhibitors with brain permeability[4]
Thiazolidinedione derivatives as 15-PGDH inhibitors[5]
Radio-sensitizing agents[6]
The product has been used as a substrate (at 40 °C and pH 9.0) to determine the D-hydantoinase activity in adzuki bean extract.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Y Thirupathi Reddy et al.
Bioorganic & medicinal chemistry letters, 20(2), 600-602 (2009-12-17)
A series of (Z)-5-((N-benzyl-1H-indol-3-yl)methylene)imidazolidine-2,4-dione (9a-9m) and 5-((N-benzyl-1H-indol-3-yl)methylene)pyrimidine-2,4,6(1H,3H,5H)-trione (10a-10i) derivatives that incorporate a variety of aromatic substituents in both the indole and N-benzyl moieties have been synthesized. These analogs were evaluated for their radiosensitization activity against the HT-29 cell line. Three
Effect of treatment with compressed CO2 and propane on D-hydantoinase activity
Andrade JM, et al.
Journal of Supercritical Fluids, 46(2), 342-350 (2008)
June Izquierdo et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 25(53), 12431-12438 (2019-07-19)
A bifunctional amine/squaramide catalyst promoted direct aldol addition of an hydantoin surrogate to pyridine 2-carbaldehyde N-oxides to afford adducts bearing two vicinal tertiary/quaternary carbons in high diastereo- and enantioselectivity (d.r. up to >20:1; ee up to 98 %) is reported. Acid
Lixuan Zhan et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(1), 1313-1329 (2018-08-28)
Hypoxic preconditioning (HPC) alleviates the selective and delayed neuronal death in the hippocampal CA1 region induced by transient global cerebral ischemia (tGCI). This type of cell death may include different programmed cell death mechanisms, namely, apoptosis and necroptosis. Although apoptotic
Ying Wu et al.
Bioorganic & medicinal chemistry, 18(4), 1428-1433 (2010-02-04)
Prostaglandins have a short life in vivo because they are metabolized rapidly by oxidation to 15-ketoprostaglandins catalyzed by a cytosolic enzyme known as NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH). Previously, CT-8, a thiazolidinedione analogue, was found to be a potent inhibitor of
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