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Merck

P1525

trans-Platinum(II)diammine dichloride

Synonym(s):

trans-Diamminedichloroplatinum(II), trans-Dichlorodiammineplatinum(II)

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About This Item

Linear Formula:
Pt(NH3)2Cl2
CAS Number:
14913-33-8
Molecular Weight:
300.05
NACRES:
NA.23
PubChem Substance ID:
57654502
UNSPSC Code:
12352302
EC Number:
238-980-9
MDL number:
MFCD00011623
Form:
powder

Key Documents

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InChI key

LXZZYRPGZAFOLE-UHFFFAOYSA-L

InChI

1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2

SMILES string

N.N.Cl[Pt]Cl

form

powder

mp

340 °C (dec.) (lit.)

application(s)

PEM fuel cells
homogeneous catalyst
material synthesis precursor

Quality Level

200

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1 of 4

This Item
BP544PHR32521672803
trans-Platinum(II)diammine dichloride

Sigma-Aldrich

P1525

trans-Platinum(II)diammine dichloride

Transplatin British Pharmacopoeia (BP) Reference Standard

BP544

Transplatin

Transplatin pharmaceutical secondary standard, certified reference material

Supelco

PHR3252

Transplatin

Transplatin United States Pharmacopeia (USP) Reference Standard

USP

1672803

Transplatin

form

powder

form

crystals

form

-

form

-

Quality Level

200

Quality Level

-

Quality Level

300

Quality Level

-

mp

340 °C (dec.) (lit.)

mp

340 °C (dec.) (lit.)

mp

340 °C (dec.) (lit.)

mp

340 °C (dec.) (lit.)

pictograms

Health hazardCorrosion
GHS08,GHS05

signalword

Danger

Hazard Classifications

Eye Dam. 1 - Resp. Sens. 1 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000487499
0000487499
0000346140
0000346140
SLCB4853

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Christian G Hartinger et al.
Inorganic chemistry, 47(1), 17-19 (2007-12-11)
A proof-of-principle study on the application of a top-down electrospray ionization Fourier transform ion cyclotron resonance mass spectrometric approach for characterization of the primary binding sites of the platinum anticancer agents cisplatin, transplatin, and oxaliplatin on ubiquitin is presented. Through
Leticia Cubo et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 15(36), 9139-9146 (2009-08-06)
A novel trans-platinum(II) complex bearing one dimethylamine (dma) and one methylamine (ma) ligand, namely trans-[PtCl(2)(dma)(ma)], recently synthesised and characterised in our laboratory, displayed relevant antiproliferative properties in vitro, being more active than the parent complex, trans-[PtCl(2)(dma)(ipa)], which has isopropylamine (ipa)
Leticia Cubo et al.
Dalton transactions (Cambridge, England : 2003), (18)(18), 3457-3466 (2009-04-22)
Three (15)N-labelled trans-Pt(ii) amine complexes with isopropylamine ((15)N-ipa), methylamine ((15)N-ma) and dimethylamine ((15)N-dma) have been prepared and characterized. 2D [(1)H,(15)N] HSQC NMR spectroscopy was used to obtain the rate and equilibrium constants for the aquation of trans-[PtCl(2)((15)N-ipa)((15)N-ma)] ((15)N-1), trans-[PtCl(2)((15)N-dma)((15)N-ma)] ((15)N-2)
Andrei V Karotki et al.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 14(7), 1129-1138 (2009-06-19)
Human metallothioneins, small cysteine- and metal-rich proteins, play an important role in the acquired resistance to platinum-based anticancer drugs. These proteins contain a M(II)4(CysS)11 cluster and a M(II)3(CysS)9 cluster localized in the alpha-domain and the beta-domain, respectively. The noninducible isoform
Angela Casini et al.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 14(5), 761-770 (2009-03-17)
Electrospray ionisation mass spectrometry was used to analyse the reactions of metal compounds with mixtures of selected proteins. Three representative medicinally relevant compounds, cisplatin, transplatin and the organometallic ruthenium compound RAPTA-C, were reacted with a pool of three proteins, ubiquitin
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