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Merck

112763

Diphenylamine

99%, ReagentPlus®

Synonym(s):

N-Phenylbenzenamine, DBA, DFA, DPA

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100 G

CZK 1,623.50

1 KG

CZK 4,540.00

CZK 1,623.50

List PriceCZK 1,910.00Save 15%

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About This Item

Linear Formula:
(C6H5)2NH
CAS Number:
Molecular Weight:
169.22
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
204-539-4
MDL number:
Beilstein/REAXYS Number:
508755

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Product Name

Diphenylamine, ReagentPlus®, 99%

InChI key

DMBHHRLKUKUOEG-UHFFFAOYSA-N

InChI

1S/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H

SMILES string

N(c1ccccc1)c2ccccc2

vapor density

5.82 (vs air)

vapor pressure

1 mmHg ( 108 °C)

product line

ReagentPlus®

assay

99%

autoignition temp.

1175 °F

bp

302 °C (lit.)

mp

50-53 °C (lit.)

solubility

water: insoluble

Quality Level

Gene Information

human ... UGT1A4(54657)

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1 of 4

This Item
24258633149CRM69121
assay

99%

assay

≥99%

assay

≥98% (GC)

assay

-

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

300

solubility

water: insoluble

solubility

alcohol: passes test

solubility

-

solubility

-

bp

302 °C (lit.)

bp

302 °C (lit.)

bp

302 °C (lit.)

bp

302 °C (lit.)

mp

50-53 °C (lit.)

mp

50-53 °C (lit.)

mp

50-53 °C (lit.), 52.5-54.0 °C

mp

50-53 °C (lit.)

vapor density

5.82 (vs air)

vapor density

5.82 (vs air)

vapor density

5.82 (vs air)

vapor density

5.82 (vs air)

Application

Diphenylamine may be used in the preparation of diphenylamine reagent, which is employed for the quantitative estimation of nucleic acid (DNA) from various biological sources by colorimetric method.[1][2] It may be used in the preparation of poly(diphenylamine), via electrochemical and chemical polymerization methods.[3] It can also be used as an internal standard in the determination of hair nicotine via gas chromatography coupled with mass spectrometry.[4]

General description

Diphenylamine, a secondary aromatic amine, is an N-substituted derivative of aniline.[3]

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

target_organs

Kidney,Liver,spleen

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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An improved diphenylamine method for the estimation of deoxyribonucleic acid.
Giles KW and Myers A.
Nature, 206(4979) , 93-93 (1965)
"Determination of hair nicotine by gas chromatography?mass spectrometry"
Man NC, et al
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 877(03), 339-342 (2009)
Soluble and methane sulfonic acid doped poly (diphenylamine)-synthesis and characterization.
Wen T-C, et al.
Materials Letters, 57(2), 280-290 (2002)
A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid.
K BURTON
The Biochemical journal, 62(2), 315-323 (1956-02-01)
Karen E Sheppard et al.
European journal of cancer (Oxford, England : 1990), 49(18), 3936-3944 (2013-09-10)
Ovarian cancer is the major cause of death from gynaecological malignancy with a 5year survival of only ∼30% due to resistance to platinum and paclitaxel-based first line therapy. Dysregulation of the phosphoinositide 3-kinase/mammalian target of rapamycin (PI3K/mTOR) and RAS/extracellular signal-regulated

Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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