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Merck

A92902

L-Ascorbic acid

99%

Synonym(s):

L-Threoascorbic acid, Antiscorbutic factor, Vitamin C

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25 G

CZK 675.00

100 G

CZK 1,190.00

500 G

CZK 3,870.00

2 KG

CZK 12,600.00

CZK 675.00


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About This Item

Empirical Formula (Hill Notation):
C6H8O6
CAS Number:
Molecular Weight:
176.12
UNSPSC Code:
12352205
NACRES:
NA.21
PubChem Substance ID:
EC Number:
200-066-2
Beilstein/REAXYS Number:
84272
MDL number:

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Product Name

L-Ascorbic acid, 99%

InChI key

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

InChI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

SMILES string

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

biological source

synthetic

assay

99%

form

powder

optical activity

[α]25/D 19.0 to 23.0°, c = 10% in H2O

color

white to off-white

pH

1.0-2.5 (25 °C, 176 g/L in water)

mp

190-194 °C (dec.)

solubility

water: soluble 176 g/L at 20 °C

Quality Level

Gene Information

human ... SLC23A2(9962)

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1 of 4

This Item
9521025556495212
assay

99%

assay

≥99.0% (RT)

assay

≥99%

assay

99.0-100.5%

biological source

synthetic

biological source

synthetic (Organic)

biological source

-

biological source

synthetic

form

powder

form

powder or crystals (possibly with chunks)

form

crystals or granules, powder or chunks

form

solid

solubility

water: soluble 176 g/L at 20 °C

solubility

H2O: 50 mg/mL at 20 °C, clear, almost colorless

solubility

water: soluble 176 g/L at 20 °C

solubility

water: soluble 176 g/L at 20 °C

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

mp

190-194 °C (dec.)

mp

190-194 °C (dec.)

mp

190-194 °C (dec.)

mp

190-194 °C (dec.)

Application

L-Ascorbic acid has been used:
  • as a component in osteogenic differentiation medium[1]
  • in MesenCult medium for the differentiation of bone marrow stromal cells[2]
  • as a standard for vitamin C assay[3]
  • to prevent trihalomethanes formation potential (THMFP)[4]

Biochem/physiol Actions

L-Ascorbic acid (L-AA) is a widely available and water-soluble compound. L-AA has an ability to inhibit the corrosion of mild steel.[5]
Ascorbic Acid, also known as Vitamin C, is a six-carbon lactone produced by plants and some animal species but not by humans and other primates. Ascorbic acid functions as an enzymatic cofactor for multiple enzymes, serving as an electron donor for monooxygenases and dioxygenases. Ascorbic acid also functions as a powerful antioxidant, particularly in regards to reactive oxygen species.

General description

L-ascorbic acid is used as a food additive, browning inhibitor, flavor stabilizer, dough modifier and color stabilizer. Deficiency of ascorbic acid is associated with scurvy. L-ascorbic acid stimulates immune response and is implicated in the synthesis of collagen, carnitine and neurotransmitters.[6]

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Certificates of Analysis (COA)

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THMs Precursor Removal Efficiency from Different Wastewater Treatment Technologies Effluents
Qurie M, et al.
Journal of Water Resource and Protection, 10(07), 637-637 (2018)
The Role of Melatonin Preconditioning on Survival of Bone Marrow-Derived Mesenchymal Stem Cells in Differentiation to Osteoblasts
Rafat A, et al.
Iranian Red Crescent Medical Journal (2018)
Evaluation of the inhibitor effect of L-ascorbic acid on the corrosion of mild steel
Ferreira ES, et al.
Materials Chemistry and Physics, 83(1) (2004)
Vitamin C in human health and disease is still a mystery? An overview
Naidu KA
Nutrition Journal, 2(1), 7-7 (2003)
Nutrient oxidation in pork loin is influenced by feed supplementation and packing methods
Godziszewska J, et al.
J. Food Compos. Anal., 56, 18-24 (2017)

Protocols

Kultivační protokoly krok za krokem pro kultivaci nervových kmenových buněk včetně izolace, expanze, diferenciace a charakterizace NSC.

Step-by-step culture protocols for neural stem cell culture including NSC isolation, expansion, differentiation and characterization.

Questions

1–3 of 3 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  3. What is the validity period of this reagent?

    1 answer
    1. This product is not assigned an expiration date or recommended retest date. Customers should routinely inspect products with no expiration date or recommended retest date to ensure they perform as expected. These products are also subject to a one-year warranty from the date of shipment.

      For more information, you may access the "Product Dating Information" document under "ADDITIONAL USEFUL DOCUMENTS ABOUT OUR PRODUCTS" at the bottom of the Quality Services page with this link: https://www.sigmaaldrich.com/life-science/quality-and-regulatory-management/quality-services.

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