Skip to Content
Merck

95220

Ergocalciferol

≥98.0% (sum of enantiomers, HPLC)

Synonym(s):

Calciferol, Ercalciol, Ergosterol irradiated, Irradiated ergosterol, Vitamin D2

Sign In to View Organizational & Contract Pricing.

Select a Size

1 G

CZK 2,720.00

5 G

CZK 8,950.00

CZK 2,720.00


Please contact Customer Service for Availability

Request a Bulk Order

About This Item

Empirical Formula (Hill Notation):
C28H44O
CAS Number:
Molecular Weight:
396.65
NACRES:
NA.79
PubChem Substance ID:
eCl@ss:
34058017
UNSPSC Code:
12352205
EC Number:
200-014-9
MDL number:
Beilstein/REAXYS Number:
1916682

Skip To

Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Ergocalciferol, ≥98.0% (sum of enantiomers, HPLC)

InChI key

MECHNRXZTMCUDQ-RKHKHRCZSA-N

InChI

1S/C28H44O/c1-19(2)20(3)9-10-22(5)26-15-16-27-23(8-7-17-28(26,27)6)12-13-24-18-25(29)14-11-21(24)4/h9-10,12-13,19-20,22,25-27,29H,4,7-8,11,14-18H2,1-3,5-6H3/b10-9+,23-12+,24-13-/t20-,22+,25-,26+,27-,28+/m0/s1

SMILES string

CC(C)[C@@H](C)/C=C/[C@@H](C)[C@@]1([H])CC[C@@]([C@]1(C)CCC/2)([H])C2=C\C=C(C[C@@H](O)CC3)/C3=C

biological source

synthetic

assay

≥98.0% (sum of enantiomers, HPLC)

form

powder

optical activity

[α]20/D +105±2°, c = 4% in ethanol

color

colorless to white

mp

114-118 °C (lit.)
114-118 °C

storage temp.

2-8°C

Quality Level

Gene Information

human ... VDR(7421)

Looking for similar products? Visit Product Comparison Guide

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
E0900000E57501239005
assay

≥98.0% (sum of enantiomers, HPLC)

assay

-

assay

≥97%

assay

-

biological source

synthetic

biological source

synthetic

biological source

synthetic (organic)

biological source

-

form

powder

form

solid

form

powder

form

-

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−20°C

mp

114-118 °C (lit.)

mp

114-118 °C (lit.)

mp

114-118 °C (lit.)

mp

114-118 °C (lit.)

Quality Level

100

Quality Level

-

Quality Level

200

Quality Level

-

Application

Ergocalciferol has been used as a standard to measure vitamin D3 levels in food samples.[1]

Biochem/physiol Actions

Ergocalciferol (vitamin D2) and 25-Hydroxycholecalciferol (vitamin D3) are the two form of vitamin D which are activated in vivo by hydroxylation.[2] Vitamin D2 and D3 may be used in a wide range of studies to assess their effects on function such as immune function and calcium homeostasis.
Ergocalciferol (vitamin D2) has less potential than cholecalciferol (vitamin D3) in treating vitamin deficiency related disorders in humans.[3] Supplementation of adequate dose of vitamin D2 prevents infantile rickets and is capable of curing adult osteomalacia.[4]

General description

Ergocalciferol is one of the two forms of supplemental vitamin D available. It is a fat-soluble vitamin.[4][5]
Ergocalciferol or viosterol is obtained from irradiated ergosterol. It represents plant source of vitamin D.[6]

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - STOT RE 1 Oral

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Development and validation of control materials for the measurement of vitamin D 3 in selected US foods
Katherine Phillips
J. Food Compos. Anal., 21(7), 527-534 (2008)
Vitamin D2 is much less effective than vitamin D3 in humans
Armas LAG, et al.
The Journal of Clinical Endocrinology and Metabolism, 89(11), 5387-5391 (2004)
Lisa A Houghton et al.
The American journal of clinical nutrition, 84(4), 694-697 (2006-10-07)
Supplemental vitamin D is available in 2 distinct forms: ergocalciferol (vitamin D2) and cholecalciferol (vitamin D3). Pharmacopoeias have officially regarded these 2 forms as equivalent and interchangeable, yet this presumption of equivalence is based on studies of rickets prevention in
Denise R. Ferrier
Biochemistry, 386-386 (2013)
The influence of the menstruum on the effectiveness of vitamin D obtained from the livers of the percomorphi order of fish
Lewis JM
The Journal of Pediatrics, 14(5), 559-569 (1939)

Questions

1–3 of 3 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. What is the recommended method for storing stock solutions of item 95220, Ergocalciferol dissolved in ethanol?

    1 answer
    1. For short-term storage (days to weeks), it is recommended to store the stock solution of item 95220, Ergocalciferol dissolved in ethanol, at 0 - 4°C. For long-term storage, the stock solution should be sealed and stored below -20°C. Typically, the stock solution can be kept for several months. Before use, it is advisable to allow the vial to reach room temperature for at least an hour.

      Helpful?

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service