F4928

Flavin-Containing Monooxygenase-1, Microsomes human

recombinant, expressed in baculovirus infected insect cells, buffered aqueous solution

• Synonym(s): FMO-1
• EC Number: 1.14.13.8 (BRENDA, IUBMB)
• NACRES: NA.54
• UNSPSC Code: 12352204
• Specific activity: See COA for Value
• Recombinant: expressed in baculovirus infected insect cells

Properties

• recombinant: expressed in baculovirus infected insect cells
• Quality Segment: 200
• form: buffered aqueous solution
• specific activity: See COA for Value
• mol wt: 55-60 kDa
• packaging: vial of 2.5 mg
• UniProt accession no.: Q01740
• shipped in: dry ice
• storage temp.: −70°C
• Gene Information: human ... FMO1(2326)

Description

Biochem/physiol Actions

The FMO′s are responsible for catalyzing the oxygenation of a variety of xenobiotic and drug compounds including environmental pollutants and carcinogens which contain a nucleophilic nitrogen, sulfur, selenium, or phosphorus-containing moiety associated with their respective oxides. These enzymes are classified as Phase I or oxidative drug metabolism enzymes.

Physical form

Solution in 100 mM potassium phosphate buffer, pH 7.4.

Other Notes

One unit will catalyze the production of 1.0 picomole of methyl p-tolylsulfoxide from methyl p-tolyl sulfide per minute at pH 9.5 at 37 deg C.

Safety Information

• Storage Class: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• PPE (personal protective equipment): Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)