197777

2-(p-Chlorophenoxy)-2-methylpropionic acid

Name: 2-(<I>p</I>-Chlorophenoxy)-2-methylpropionic acid
Brand: ALDRICH
Price: 81 EUR
Availability: InStock

97%

Synonym(s):

α-(p-Chlorophenoxy)isobutyric acid, Clofibric acid

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50 G

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About This Item

Linear Formula:

ClC₆H₄OC(CH₃)₂CO₂H

CAS Number:

882-09-7

Molecular Weight:

214.65

NACRES:

NA.22

PubChem Substance ID:

24851846

UNSPSC Code:

12352100

EC Number:

212-925-9

MDL number:

MFCD00004192

Key Documents

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Product Name

2-(p-Chlorophenoxy)-2-methylpropionic acid, 97%

InChI key

TXCGAZHTZHNUAI-UHFFFAOYSA-N

InChI

1S/C10H11ClO3/c1-10(2,9(12)13)14-8-5-3-7(11)4-6-8/h3-6H,1-2H3,(H,12,13)

SMILES string

CC(C)(Oc1ccc(Cl)cc1)C(O)=O

assay

97%

mp

120-122 °C (lit.)

functional group

carboxylic acid
chloro

Quality Level

200

Gene Information

human ... PPARA(5465), PPARG(5468)
mouse ... Ppara(19013), Pparg(19016)

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Show Differences

1 of 4

This Item	270792	K401	159549
Sigma-Aldrich 197777 2-(p-Chlorophenoxy)-2-methylpropionic acid	Sigma-Aldrich 270792 4-(Chloromethyl)benzoic acid	Sigma-Aldrich K401 2-Ketobutyric acid	Sigma-Aldrich 159549 4-(Bromomethyl)benzoic acid
assay 97%	assay 95%	assay 97%	assay 97%
Quality Level 200	Quality Level 200	Quality Level 100	Quality Level 200
mp 120-122 °C (lit.)	mp 201-202 °C (lit.)	mp 30-34 °C (lit.)	mp 224-229 °C (lit.)
functional group carboxylic acid	functional group carboxylic acid, chloro	functional group -	functional group bromo, carboxylic acid
Gene Information human ... PPARA(5465), PPARG(5468) mouse ... Ppara(19013), Pparg(19016)	Gene Information -	Gene Information -	Gene Information -

pictograms

GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Reactive tracer test to evaluate the fate of pharmaceuticals in rivers.

Uwe Kunkel et al.

Environmental science & technology, 45(15), 6296-6302 (2011-06-16)

The fate of pharmaceutically active substances in rivers is still only incompletely understood, especially as the knowledge transfer from laboratory experiments to the real world is complicated by factors like turbidity, hydrodynamics, or heterogeneity. Therefore, we performed a tracer test

Ecotoxicological impacts of clofibric acid and diclofenac in common carp (Cyprinus carpio) fingerlings: hematological, biochemical, ionoregulatory and enzymological responses.

Manoharan Saravanan et al.

Journal of hazardous materials, 195, 188-194 (2011-09-03)

Investigation on the toxic effects of pharmaceutical drugs namely clofibric acid (CA) and diclofenac (DCF) were studied in a common carp Cyprinus carpio at different concentrations such as 1, 10 and 100 μg L(-1) for a short-term period of 96

Biodegradation of clofibric acid and identification of its metabolites.

R Salgado et al.

Journal of hazardous materials, 241-242, 182-189 (2012-10-16)

Clofibric acid (CLF) is the pharmaceutically active metabolite of lipid regulators clofibrate, etofibrate and etofyllinclofibrate, and it is considered both environmentally persistent and refractory. This work studied the biotransformation of CLF in aerobic sequencing batch reactors (SBRs) with mixed microbial

Removal of carbamazepine and clofibric acid from water using double templates-molecularly imprinted polymers.

Chao-meng Dai et al.

Environmental science and pollution research international, 20(8), 5492-5501 (2013-02-26)

A novel double templates-molecularly imprinted polymer (MIP) was prepared by precipitation polymerization using carbamazepine (CBZ) and clofibric acid (CA) as the double templates molecular and 2-vinylpyridine as functional monomer. The equilibrium data of MIP was well described by the Freundlich

Inhibition of animal acetyl-coenzyme A carboxylase by 2-(p-chlorophenoxy)-2-methylpropionic acid and 2-ethylhexanoic acid.

K Sumida et al.

Chemosphere, 33(11), 2201-2207 (1996-12-01)

Peroxisome proliferators are generally known as activators of fatty acid beta-oxidation which is one of degradation pathways. However, since it is unknown whether peroxisome proliferators have an effect on biosynthesis of fatty acid or not, we commenced to study if

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2-(p-Chlorophenoxy)-2-methylpropionic acid