Skip to Content
Merck

14-251-M

p38α/SAPK2a Protein, active, 10 µg

Active, N-terminal GST tagged, recombinant, full length p38α/SAPK2a, for use in Kinase Assays.

Slide 1 of 1
Sign In to View Organizational & Contract Pricing

Select a Size

14-251

€569.00

14-251M

€3,610.00

€569.00

Check Cart for Availability
Request a Bulk Order

About This Item

UNSPSC Code:
12352202
eCl@ss:
32160405
NACRES:
NA.41

Key Documents

View All Documentation

Skip To

Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

biological source

human

Quality Level

100

recombinant

expressed in E. coli

mol wt

Mw 67.7 kDa

manufacturer/tradename

Upstate®

technique(s)

activity assay: suitable (kinase)

NCBI accession no.

NM_001315.1
NM_139012.1
NM_139013.1
NM_139014.1

UniProt accession no.

Q16539

Gene Information

human ... MAPK14(1432)

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
14-249-M14-687-M14-329-M
p38α/SAPK2a Protein, active, 10 µg Active, N-terminal GST tagged, recombinant, full length p38α/SAPK2a, for use in Kinase Assays.

Sigma-Aldrich

14-251-M

p38α/SAPK2a Protein, active, 10 µg

p38δ/SAPK4 Protein, active, 10 µg Active, recombinant GST fusion protein fused to full length human p38δ/SAPK4. For use in Kinase Assays.

Sigma-Aldrich

14-249-M

p38δ/SAPK4 Protein, active, 10 µg

p38α/SAPK2a (T106M) Protein, active, 10 µg Active, N-terminal GST-tagged, recombinant, human, full-length p38α/SAPK2a containing the mutation T106M. Activated using DD-MKK6 & repurified using glutathione-agarose. For use in Kinase Assays.

Sigma-Aldrich

14-687-M

p38α/SAPK2a (T106M) Protein, active, 10 µg

JNK2α2/SAPK1a Protein, active, 10 µg Active, N-terminal His-tagged, full length human JNK2α2/SAPK1a, for use in Kinase Assays.

Sigma-Aldrich

14-329-M

JNK2α2/SAPK1a Protein, active, 10 µg

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

-

technique(s)

activity assay: suitable (kinase)

technique(s)

activity assay: suitable (kinase)

technique(s)

activity assay: suitable (kinase)

technique(s)

activity assay: suitable (kinase)

biological source

human

biological source

human

biological source

human

biological source

human

mol wt

Mw 67.7 kDa

mol wt

Mw 71 kDa

mol wt

Mw 67.7 kDa

mol wt

Mw 49.2 kDa

Gene Information

human ... MAPK14(1432)

Gene Information

-

Gene Information

human ... MAPK14(1432)

Gene Information

human ... MAPK9(5601)

UniProt accession no.

Q16539

UniProt accession no.

O15264

UniProt accession no.

Q16539

UniProt accession no.

P45984

General description

N-terminal GST tagged, recombinant, full length p38α/SAPK2a
Product Source: expressed in E. coli

Biochem/physiol Actions

Protein Target: p38α/SAPK2a
Target Sub-Family: CMGC

Packaging

Also available in 250μg size (2x125μg) - Call for pricing and availability. Please reference catalog number 14-251M when ordering the 250μg size.

Physical form

Glutathione-agarose

Preparation Note

6 months at -20°C

Analysis Note

Routinely evaluated by phosphorylation of MBP

Other Notes

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H317

Hazard Classifications

Skin Sens. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Y N Doza et al.
FEBS letters, 364(2), 223-228 (1995-05-08)
A MAP kinase homologue, termed the reactivating kinase (RK), lies in a signalling pathway which mediates cellular responses to stress. Here we demonstrate that the stress-induced activation of the RK in human KB cells is accompanied by the phosphorylation of
A single autophosphorylation site confers oncogenicity to the Neu/ErbB-2 receptor and enables coupling to the MAP kinase pathway.
Ben-Levy, R, et al.
The Embo Journal, 13, 3302-3311 (1994)
A Cuenda et al.
FEBS letters, 364(2), 229-233 (1995-05-08)
A class of pyridinyl imidazoles inhibit the MAP kinase homologue, termed here reactivating kinase (RK) [Lee et al. (1994) Nature 372, 739-746]. We now show that one of these compounds (SB 203580) inhibits RK in vitro (IC50 = 0.6 microM)

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service