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F8775

Sigma-Aldrich

Formaldehyde solution

for molecular biology, 36.5-38% in H2O

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Synonym(s):
Formalin
Linear Formula:
HCHO
CAS Number:
Molecular Weight:
30.03
Beilstein:
1209228
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.31

grade

for molecular biology

Quality Level

vapor density

1.03 (vs air)

vapor pressure

52 mmHg ( 37 °C)

form

liquid

autoignition temp.

572 °F

contains

10-15% methanol

concentration

36.5-38% in H2O

technique(s)

ChIP: suitable
immunofluorescence: suitable
immunohistochemistry: suitable

density

1.09 g/mL at 25 °C (lit.)

suitability

suitable for (use in Formaldehyde-Agarose Gel Electrophoresis of RNA)

application(s)

general analytical
genomic analysis

storage temp.

15-25°C

SMILES string

[H]C([H])=O

InChI

1S/CH2O/c1-2/h1H2

InChI key

WSFSSNUMVMOOMR-UHFFFAOYSA-N

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This Item
2525491551247083-U
vibrant-m

F8775

Formaldehyde solution

vibrant-m

252549

Formaldehyde solution

vibrant-m

15512

Formaldehyde solution

vibrant-m

47083-U

Formaldehyde solution

grade

for molecular biology

grade

ACS reagent

grade

-

grade

certified reference material

form

liquid

form

liquid

form

-

form

-

vapor density

1.03 (vs air)

vapor density

1.03 (vs air)

vapor density

1.03 (vs air)

vapor density

1.03 (vs air)

autoignition temp.

572 °F

autoignition temp.

572 °F

autoignition temp.

572 °F

autoignition temp.

572 °F

density

1.09 g/mL at 25 °C (lit.)

density

1.09 g/mL at 25 °C (lit.)

density

1.09 g/mL at 25 °C (lit.)

density

1.09 g/mL at 25 °C (lit.)

General description

Formaldehyde, a colorless, pungent-smelling chemical, finds extensive application in various biological research and laboratory settings. Primarily supplied as a 37% solution (formalin), its diverse uses range from tissue preservation and sterilization to acting as a denaturant in RNA gel electrophoresis. However, it′s crucial to acknowledge its potential health risks and handle it with appropriate precautions.Multifaceted Functions:
  • Preservative: Formaldehyde′s ability to inhibit microbial growth makes it an effective preservative in biological samples, preventing decay and ensuring their integrity for further analysis. This property finds application in medical laboratories, museums, and even embalming fluids.
  • Fixative: In histology, formaldehyde acts as a fixative, cross-linking proteins and preserving tissue structures for microscopic examination. This allows researchers to visualize anatomical details and cellular components with remarkable clarity.
  • Denaturant: In molecular biology techniques like formaldehyde-agarose gel electrophoresis, formaldehyde denatures RNA molecules, preventing them from forming secondary structures and enabling size-based separation. This technique proves invaluable for studying gene expression and RNA integrity.

Application

Formaldehyde solution has been used for fixing of cells and tissue sections. It has been used in the formaldehyde agarose gel electrophoresis. Formaldehyde is used as a denaturant in formaldehyde-agarose gel electrophoresis of RNA.

Features and Benefits

  • Versatile and adaptable for a wide variety of laboratory and research applications
  • Suitable for Molecular Biology and Biochemical applications

Analysis Note

Tested for use in formaldehyde-agarose gel electrophoresis of RNA.

Other Notes

For additional information on our range of Biochemicals, please complete this form.

comparable product

Product No.
Description
Pricing

Signal Word

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Flam. Liq. 3 - Muta. 2 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

133.0 °F - closed cup

Flash Point(C)

56.11 °C - closed cup


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

EU REACH Annex XVII (Restriction List)


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