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Merck

I5161

Iodoacetamide

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25 G

2.400,00 kr.

100 G

7.370,00 kr.

10 KG

65.110,00 kr.

2.400,00 kr.

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About This Item

Linear Formula:
ICH2CONH2
CAS Number:
144-48-9
Molecular Weight:
184.96
EC Number:
205-630-1
UNSPSC Code:
12352202
NACRES:
NA.21
Beilstein/REAXYS Number:
1739080
MDL number:
MFCD00008028

Key Documents

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InChI

1S/C2H4INO/c3-1-2(4)5/h1H2,(H2,4,5)

InChI key

PGLTVOMIXTUURA-UHFFFAOYSA-N

SMILES string

NC(=O)CI

biological source

synthetic

assay

≥99% (NMR)

form

powder

mp

92-95 °C (lit.)

solubility

H2O: 0.5 M, clear, colorless

suitability

suitable for manufacturing use

storage temp.

2-8°C

Quality Level

400

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Show Differences

1 of 4

This Item
A3221I6125I1149
Iodoacetamide

SAFC

I5161

Iodoacetamide

Iodoacetamide Single use vial of 56 mg

Sigma-Aldrich

A3221

Iodoacetamide

Iodoacetamide ≥99% (NMR), crystalline

Sigma-Aldrich

I6125

Iodoacetamide

Iodoacetamide BioUltra

Sigma-Aldrich

I1149

Iodoacetamide

form

powder

form

powder

form

crystalline

form

powder

biological source

synthetic

biological source

synthetic (organic)

biological source

synthetic (organic)

biological source

synthetic (organic)

assay

≥99% (NMR)

assay

≥99% (HPLC)

assay

≥99% (NMR)

assay

≥99% (NMR)

suitability

suitable for manufacturing use

suitability

suitable for LC-MS

suitability

-

suitability

-

mp

92-95 °C (lit.)

mp

92-95 °C (lit.)

mp

92-95 °C (lit.)

mp

92-95 °C (lit.)

solubility

H2O: 0.5 M, clear, colorless

solubility

H2O: soluble 50 mg/mL, clear, colorless to faintly yellow

solubility

H2O: soluble 0.5 M, clear, colorless

solubility

H2O: 0.5 M, clear, colorless

Biochem/physiol Actions

Iodoacetamide acts as an alkylating reagent for cysteine residues in peptide sequencing. It is an irreversible inhibitor of enzymes with cysteine at the active site. It reacts much more slowly with histidine residues, but that activity is responsible for inhibiting ribonuclease.

General description

Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.

Legal Information

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Chronic 4 - Resp. Sens. 1 - Skin Sens. 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000518752
0000518753
0000518753
0000518752
0000505428

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Valentina R Minciacchi et al.
Oncotarget, 6(13), 11327-11341 (2015-04-11)
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Mia Jüllig et al.
PloS one, 9(5), e96489-e96489 (2014-05-08)
Bypass of foregut secreted factors promoting insulin resistance is hypothesized to be one of the mechanisms by which resolution of type 2 diabetes (T2D) follows roux-en-y gastric bypass (GBP) surgery. To identify insulin resistance-associated proteins and metabolites which decrease more
Jeremy Rouillon et al.
Neuromuscular disorders : NMD, 24(7), 563-573 (2014-05-13)
Diagnosis of muscular dystrophies is currently based on invasive methods requiring muscle biopsies or blood tests. The aim of the present study was to identify urinary biomarkers as a diagnostic tool for muscular dystrophies. Here, the urinary proteomes of Duchenne
Elena B Lugli et al.
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Smoking is a well-established risk factor for rheumatoid arthritis (RA), and it has been proposed that smoking-induced citrullination renders autoantigens immunogenic. To investigate this mechanism, we examined human lung tissue from 40 subjects with defined smoking status, with or without
Francesco Trepiccione et al.
Kidney international, 86(4), 757-767 (2014-05-03)
Almost half of patients receiving lithium salts have nephrogenic diabetes insipidus. Chronic lithium exposure induces AQP2 downregulation and changes in the cellular composition of the collecting duct. In order to understand these pathophysiological events, we determined the earliest lithium targets
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