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P9159

Piperidine-4-sulfonic acid

Synonym(s):

P4S

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About This Item

Empirical Formula (Hill Notation):
C5H11NO3S
CAS Number:
72450-62-5
Molecular Weight:
165.21
NACRES:
NA.77
PubChem Substance ID:
24278165
UNSPSC Code:
12352106
MDL number:
MFCD00055097

Key Documents

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InChI

1S/C5H11NO3S/c7-10(8,9)5-1-3-6-4-2-5/h5-6H,1-4H2,(H,7,8,9)

SMILES string

OS(=O)(=O)C1CCNCC1

InChI key

UGBJGGRINDTHIH-UHFFFAOYSA-N

form

powder

Quality Level

200

Gene Information

human ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562)

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This Item
D1262P9625D2531
Piperidine-4-sulfonic acid

Sigma-Aldrich

P9159

Piperidine-4-sulfonic acid

P1,P4-Di(adenosine-5′) tetraphosphate ammonium salt ≥95% (HPLC), powder

Sigma-Aldrich

D1262

P1,P4-Di(adenosine-5′) tetraphosphate ammonium salt

Phenazine methosulfate

Sigma-Aldrich

P9625

Phenazine methosulfate

Dextromethorphan hydrobromide monohydrate ≥99% (TLC)

Sigma-Aldrich

D2531

Dextromethorphan hydrobromide monohydrate

form

powder

form

powder

form

powder

form

powder

Gene Information

human ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562)

Gene Information

human ... PLD1(5337), PLD2(5338), PLD3(23646), PLD4(122618), PLD5(200150)

Gene Information

-

Gene Information

human ... GRIN1(2902), GRIN2A(2903), GRIN2B(2904), GRIN2C(2905), GRIN2D(2906), GRIN3A(116443), GRIN3B(116444), SIGMAR1(10280)

Biochem/physiol Actions

GABAA receptor agonist.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000379482
0000379482
0000300095
0000300095
0000234465

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G Maksay et al.
European journal of pharmacology, 411(1-2), 55-60 (2001-01-04)
In order to study the correlation of the thermodynamic driving forces of binding with the efficacies of displacing ligands, the specific binding of [3H]SR 95531 [2-(3-carboxypropyl)3-amino-6-p-methoxyphenylpyridazinium bromide], a GABA(A) receptor antagonist, was studied in cell lines stably expressing human alpha(1)beta(3)gamma(2)
B Ebert et al.
Molecular pharmacology, 46(5), 957-963 (1994-11-01)
Using systematic combination of alpha 1, alpha 3, and alpha 5 with beta 1, beta 2, and beta 3, together with gamma 1, gamma 2, and gamma 3, we have investigated the contributions of the various alpha, beta, and gamma
Kate K O'Toole et al.
Molecular pharmacology, 81(2), 189-197 (2011-11-02)
The GABA type A receptor (GABA(A)R) is expressed ubiquitously throughout the brain and is a target for many therapeutic agents, including general anesthetics and benzodiazepines, which enhance receptor function by increasing the open probability (P(o)) of the ion channel. It
G Akk et al.
The Journal of physiology, 532(Pt 3), 673-684 (2001-04-21)
Neurosteroids are produced in the brain, and can have rapid actions on membrane channels of neurons. Pregnenolone sulfate (PS) is a sulfated neurosteroid which reduces the responses of the [gamma]-aminobutyric acid A (GABA(A)) receptor. We analysed the actions of PS
Norbert Topf et al.
Anesthesiology, 98(2), 306-311 (2003-01-29)
Volatile anesthetics prolong inhibitory postsynaptic potentials in central neurons an allosteric action on the gamma-aminobutyric acid type A (GABA(A)) receptor, an effect that may underlie the hypnotic actions of these agents. Inhaled anesthetics such as isoflurane act to enhance responses
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