GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
Synonyms:
ECA4, EJM, EJM5
Species:
Human GABRA1 (2554), Mouse Gabra1 (14394), Rat Gabra1 (29705), domestic guinea pig Gabra1 (100721626), cow GABRA1 (780973), dog GABRA1 (489143), naked mole-rat Gabra1 (101719179), Zebrafish gabra1 (768183), sheep GABRA1 (101117759), chicken GABRA1 (374214)
UniProtKB ID:
Gene ID:
- Human(2554) Summary: This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
- Mouse(14394) gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
- Rat(29705) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- domestic guinea pig(100721626) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- cow(780973) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- dog(489143) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- naked mole-rat(101719179) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- Zebrafish(768183) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- sheep(101117759) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- chicken(374214) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- domestic cat(100286792) gamma-aminobutyric acid (GABA) A receptor, alpha 1
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Small Molecule - Agonist
Small Molecule - Allosteric Modulator
Product Number
Description
Species
Zolpidem for system suitability, CRS, European Pharmacopoeia (EP) Reference Standard,
Species
human
Chlordiazepoxide hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human
Small Molecule - Antagonist
Product Number
Description
Species
Acamprosate calcium, United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 400.48 (C10H20CaN2O8S2),
Species
human
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-GABA A Receptor β2/3 Antibody, clone 62-3G1, Upstate®, from mouse,
Species Reactivity
bovine, human, rat
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-GABA (No Gluteraldehyde) Antibody, Chemicon®, from rabbit,
Species Reactivity
rat
Application
immunohistochemistry
Anti-GABA A Receptor α1 chain Antibody, NT, clone BD24, clone BD24, Chemicon®, from mouse,
Species Reactivity
avian, bovine, human, pig
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-GABA Antibody, serum, Chemicon®,
Species Reactivity
all, rat
Application
ELISA
immunohistochemistry
immunohistochemistry
Anti-GABA Antibody, clone 5A9, clone 5A9, Chemicon®, from mouse,
Species Reactivity
mammals
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Inhibitor
Product Number
Description
Species
Small Molecule - Ligand
Product Number
Description
Species
Small Molecule - Mixed Agonist/Antagonist
Product Number
Description
Species
Phenol solution, Equilibrated with 10 mM Tris HCl, pH 8.0, 1 mM EDTA, BioReagent, Molecular Biology,
Species
human