Hydroxyapatite

Name: Hydroxyapatite
Brand: ALDRICH

synthetic, 99.8% trace metals basis (excludes Mg)

Sinónimos:

Calcium hydroxyphosphate, HAp, Hydroxylapatite

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Fórmula lineal:

[Ca₅(OH)(PO₄)₃]_x

Número CAS:

12167-74-7

Peso molecular:

502.31

NACRES:

NA.23

PubChem Substance ID:

24880760

UNSPSC Code:

12352302

EC Number:

235-330-6

MDL number:

MFCD00010904

Assay:

99.8% trace metals basis (excludes Mg)

Form:

solid

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Nombre del producto

Hydroxyapatite, synthetic, 99.8% trace metals basis (excludes Mg)

InChI key

XYJRXVWERLGGKC-UHFFFAOYSA-D

InChI

1S/5Ca.3H3O4P.H2O/c;;;;;3*1-5(2,3)4;/h;;;;;3*(H3,1,2,3,4);1H2/q5*+2;;;;/p-10

SMILES string

[Ca++].[Ca++].[Ca++].[Ca++].O[Ca+].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O

assay

99.8% trace metals basis (excludes Mg)

form

solid

impurities

≤2500 ppm Trace Metal Analysis

mp

1100 °C (lit.)

application(s)

electroplating
material synthesis precursor

Quality Level

100

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Este artículo	289396	677418	924369
Sigma-Aldrich 574791 Hydroxyapatite	Sigma-Aldrich 289396 Hydroxyapatite	Sigma-Aldrich 677418 Hydroxyapatite	Sigma-Aldrich 924369 Hydroxyapatite coating powder
form solid	form powder, solid	form nanopowder, solid	form -
assay 99.8% trace metals basis (excludes Mg)	assay -	assay ≥97%	assay ≥99% trace metals basis
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
mp 1100 °C (lit.)	mp 1100 °C (lit.)	mp 1100 °C (lit.)	mp -
impurities ≤2500 ppm Trace Metal Analysis	impurities -	impurities -	impurities ≤50 ppm (Pb)

Clase de almacenamiento

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Deproteinized bovine bone functionalized with the slow delivery of BMP-2 for the repair of critical-sized bone defects in sheep.

Tie Liu et al.

Bone, 56(1), 110-118 (2013-06-05)

As an alternative to an autologous bone graft, deproteinized bovine bone (DBB) is widely used in the clinical dentistry. Although DBB provides an osteoconductive scaffold, it is not capable of enhancing bone regeneration because it is not osteoinductive. In order

Efficacy and safety of recombinant human bone morphogenetic protein-2/calcium phosphate matrix for closed tibial diaphyseal fracture: a double-blind, randomized, controlled phase-II/III trial.

Thomas Lyon et al.

The Journal of bone and joint surgery. American volume, 95(23), 2088-2096 (2013-12-07)

Recombinant human bone morphogenetic protein-2 (rhBMP-2) applied on an absorbable collagen sponge improves open tibial fracture-healing as an adjunct to unreamed intramedullary nail fixation. We evaluated rhBMP-2 and a new, injectable calcium phosphate matrix (CPM) formulation in acute closed tibial

Autophagy induced by calcium phosphate precipitates targets damaged endosomes.

Xi Chen et al.

The Journal of biological chemistry, 289(16), 11162-11174 (2014-03-13)

Calcium phosphate precipitates (CPPs) form complexes with DNA, which enter cells via endocytosis. Under this condition CPPs induce autophagy via the canonic autophagy machinery. Here we showed that CPP-induced autophagy was also dependent on endocytosis as the process was significantly

The effect of amorphous pyrophosphate on calcium phosphate cement resorption and bone generation.

Liam M Grover et al.

Biomaterials, 34(28), 6631-6637 (2013-06-12)

Pyrophosphate ions are both inhibitors of HA formation and substrates for phosphatase enzymes. Unlike polyphosphates their hydrolysis results simultaneously in the complete loss of mineral formation inhibition and a localised elevation in orthophosphate ion concentration. Despite recent advances in our

Calcium phosphate ceramics in bone tissue engineering: a review of properties and their influence on cell behavior.

Satyavrata Samavedi et al.

Acta biomaterialia, 9(9), 8037-8045 (2013-06-25)

Calcium phosphate ceramics (CPCs) have been widely used as biomaterials for the regeneration of bone tissue because of their ability to induce osteoblastic differentiation in progenitor cells. Despite the progress made towards fabricating CPCs possessing a range of surface features

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