03-0177-00

SMC^® Human IL-17A/F Heterodimer High Sensitivity Immunoassay Kit

• Sinónimos: IL-17A/F Single Molecule Counting Kit, IL-17A/F ultra-sensitive immunoassay
• Código UNSPSC: 12161503
• NACRES: NA.84

Propiedades

• descripción: 0.60-4.69 pg/mL, refer to CoA for lot-specific LLOQ
• Línea del producto: SMC^®
• reactividad de especies: monkey, canine, nonhuman primates
• fabricante / nombre comercial: SMC^®
• assay range: sensitivity: 2.34 pg/mL; (Lower Limit of Quantification); inter-assay cv: <20%; intra-assay cv: <15%; (Intra-assay n=20; Inter-assay n=5)
• técnicas: single molecule counting: suitable
• temp. de almacenamiento: 2-8°C

Descripción

Aplicación

Inflammatory Disease / Immune Response / Autoimmune Disease

The sensitivity of the Single Molecule Counting (SMC^®) technology gives the SMC^® Human IL-17A/F High Sensitivity Immunoassay Kit unparalleled performance in the quantification of IL-17A/F in human serum and plasma.

This new streamline kit has been improved with the following features including new including new improvements over the legacy IL-17A/F kit, #03-0119-00:

• Adjusted standard curve--changed to 0.3 – 300 pg/mL from 0.59 – 600 pg/mL
• Improved options for sample prep and incubation
• Lyophilization of the standard provides the kit at one storage conditi
• Removal of a plate transfer ste• Increased reagent volumes to accommodate automation
• Validated to run on both SMCxPRO^® and Erenna

Research Category:
Inflammation & Immunology

Research Sub-Category:

• Inflammatory Disease
• Immune Response
• Autoimmune disease

Acciones bioquímicas o fisiológicas

Species Reactivity:
Although IL-17A/F was detectable in non-human primate/monkey and canine, the assay has not been validated for these species.

Accuracy:

• Minimum of 5 serum samples spiked with average recovery of 101% with a range of 91-114%
• Minimum of 5 plasma samples spiked with average recovery of 88% with a range of 75-111%

Envase

96 well assay

Nota de análisis

• Sensitivity: LLOQ 2,340 fg/mL* (SMCxPRO^® Instrument)
• Standard Curve Range: 590-600,000 fg/mL
• Intra-assay CV: <15%
• Inter-assay CV: <20%
• Linearity: Serum: 106% Plasma: 111%
• Recovery: Serum: 101% Plasma: 88%

*Indicative LLOQ created from average of 14 independent in house runs, where >80% met same value defined with CV & Recovery +/- 20%. Refer to CoA for lot specific performance.

Inflammation & ImmunologyInflammatory DiseaseImmune ResponseAutoimmune Disease

Otras notas

• Assay Buffer
• IL-17A/F Coated Beads
• Standard Diluent
• IL-17A/F Detection Antibody
• IL-17A/F Standard
• 10X Wash Buffer
• Buffer D
• Elution Buffer B

Información legal

SMC is a registered trademark of Singulex

SMCxPRO is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Pictogramas: GHS06,GHS08
• Palabra de señalización: Danger
• Frases de peligro: H302 + H332,H311,H319,H360FD,H412
• Consejos de prudencia: P273 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P308 + P313
• Clasificaciones de peligro: Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Repr. 1B
• Código de clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects