05-780

Anti-Akt3/PKBγ Antibody, clone GMA104

Name: Anti-Akt3/PKBγ Antibody, clone GMA104
Brand: MM

clone GMA104, Upstate^®, from mouse

Slide 1 of 1

Iniciar sesión para ver los posibles precios especiales de su organización

Seleccione un Tamaño

En este momento no podemos mostrarle ni los precios ni la disponibilidad

Acerca de este artículo

Código UNSPSC:

12352203

eCl@ss:

32160702

NACRES:

NA.41

Documentos clave

Ver Toda la documentación

Saltar a

Servicio técnico

¿Necesita ayuda? Nuestro equipo de científicos experimentados está aquí para ayudarle.

Permítanos ayudarle

origen biológico

mouse

Nivel de calidad

100

conjugado

unconjugated

forma del anticuerpo

purified antibody

tipo de anticuerpo

primary antibodies

clon

GMA104, monoclonal

reactividad de especies

human

fabricante / nombre comercial

Upstate^®

técnicas

immunoprecipitation (IP): suitable
western blot: suitable

isotipo

IgG2a

Nº de acceso NCBI

NM_005465

Nº de acceso UniProt

Q9Y243

Condiciones de envío

wet ice

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... AKT3(10000)

Comparar elementos similares

Ver comparación completa

Mostrar Diferencias

1 of 4

Este artículo	07-383	05-796	04-1643
Sigma-Aldrich 05-780 Anti-Akt3/PKBγ Antibody, clone GMA104	Sigma-Aldrich 07-383 Anti-Akt3/PKBγ Antibody	Sigma-Aldrich 05-796 Anti-Akt1/PKBα Antibody, clone AW24, rabbit monoclonal	Sigma-Aldrich 04-1643 Rabbit Anti-Mouse IgG Antibody, clone RM104
species reactivity human	species reactivity human	species reactivity human, mouse, rat	species reactivity mouse
antibody form purified antibody	antibody form affinity purified immunoglobulin	antibody form purified antibody	antibody form purified antibody
clone GMA104, monoclonal	clone polyclonal	clone AW24, monoclonal	clone RM104, monoclonal
biological source mouse	biological source rabbit	biological source rabbit	biological source rabbit
shipped in wet ice	shipped in dry ice	shipped in dry ice	shipped in wet ice
technique(s) immunoprecipitation (IP): suitable, western blot: suitable	technique(s) immunoprecipitation (IP): suitable, western blot: suitable	technique(s) immunoprecipitation (IP): suitable, western blot: suitable	technique(s) ELISA: suitable, western blot: suitable

Descripción general

~60kDa

Inmunógeno

peptide corresponding to amino acids 119-131 (CSPTSQIDNIGEE) of human Akt3/PKBγ

Aplicación

Research Category
Signaling

Research Sub Category
PI3K, Akt, & mTOR Signaling

This Anti-Akt3/PKBγ Antibody, clone GMA104 is validated for use in IP, WB for the detection of Akt3/PKBγ.

Acciones bioquímicas o fisiológicas

Predicted to cross-react with mouse and rat based on sequence homology.

RhoA

Forma física

Buffered solution containing 0.1M Tris-Glycine, 0.15M NaCl, 0.05% Sodium Azide, pH 7.4.

Format: Purified

Protein A purified

Nota de preparación

Stable for 1 year at 2-8°C from date of receipt.

Nota de análisis

routinely evaluated by immunoblot on RIPA lysates from Jurkat or HL-60 cells

Información legal

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

¿No encuentra el producto adecuado?

Pruebe nuestro Herramienta de selección de productos.

Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 1

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

K-Ras(V12) differentially affects the three Akt isoforms in lung and pancreatic carcinoma cells and upregulates E-cadherin and NCAM via Akt3.

Rebekka Geißert et al.

Cell communication and signaling : CCS, 22(1), 85-85 (2024-01-31)

K-Ras is the most frequently mutated Ras variant in pancreatic, colon and non-small cell lung adenocarcinoma. Activating mutations in K-Ras result in increased amounts of active Ras-GTP and subsequently a hyperactivation of effector proteins and downstream signaling pathways. Here, we

Characterization of PDK2 activity against protein kinase B gamma.

Conrad P Hodgkinson et al.

Biochemistry, 41(32), 10351-10359 (2002-08-07)

Protein kinase B (PKB), also known as Akt, is a serine/threonine protein kinase controlled by insulin, various growth factors, and phosphatidylinositol 3-kinase. Full activation of the PKB enzyme requires phosphorylation of a threonine in the activation loop and a serine

The Akt isoforms are present at distinct subcellular locations.

Santi, SA; Lee, H

American Journal of Physiology. Cell Physiology null

MicroRNA-497 impairs the growth of chemoresistant neuroblastoma cells by targeting cell cycle, survival and vascular permeability genes.

Aroa Soriano et al.

Oncotarget, 7(8), 9271-9287 (2016-01-30)

Despite multimodal therapies, a high percentage of high-risk neuroblastoma (NB) become refractory to current treatments, most of which interfere with cell cycle and DNA synthesis or function, activating the DNA damage response (DDR). In cancer, this process is frequently altered

Preguntas

Revisiones

Sin puntuación

Filtros activos

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico