407707
PhosphoDetect Anti-Insulin Receptor (pTyr1162/1163) Rabbit pAb
liquid, Calbiochem®
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Código UNSPSC:
12352203
NACRES:
NA.43
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rabbit
Nivel de calidad
tipo de anticuerpo
primary antibodies
clon
polyclonal
Formulario
liquid
contiene
≤0.1% sodium azide as preservative
reactividad de especies
human
fabricante / nombre comercial
Calbiochem®
condiciones de almacenamiento
OK to freeze
avoid repeated freeze/thaw cycles
isotipo
IgG
Condiciones de envío
wet ice
temp. de almacenamiento
−70°C
modificación del objetivo postraduccional
phosphorylation (pTyr1162/pTyr1163)
Información sobre el gen
human ... INSR(3643)
1 of 4
Este artículo | I1783 | PC635 | 527460 |
|---|---|---|---|
| biological source rabbit | biological source rabbit | biological source rabbit | biological source rabbit |
| Quality Level 100 | Quality Level 200 | Quality Level 100 | Quality Level 100 |
| species reactivity human | species reactivity human, mouse | species reactivity human | species reactivity human, mouse |
| clone polyclonal | clone polyclonal | clone polyclonal | clone polyclonal |
| shipped in wet ice | shipped in dry ice | shipped in wet ice | shipped in wet ice |
| form liquid | form buffered aqueous solution | form liquid | form liquid |
Descripción general
Note: 1 T = 1 test. Sufficient for 10 Western mini blots.
Rabbit polyclonal antibody adsorbed with non-phosphopeptide corresponding to the immunogen phosphorylation site, followed by immunoaffinity chromatography. Recognizes the insulin receptor (IR) protein phosphorylated at Tyr1162/1163 and insulin-like growth factor 1 receptor (IGF-1R) protein phosphorylated at Tyr1162/1163.
Recognizes the ~95 kDa β subunit of the insulin receptor protein phosphorylated at Tyr1162 and Tyr1163 in insulin receptor transfected cells. Cross-reacts with the insulin-like growth factor-1 receptor phosphorylated at Tyr1135 and Tyr1136.
This PhosphoDetect Anti-Insulin Receptor (pTyr1162/1163) Rabbit pAb is validated for use in ELISA, WB, ICC for the detection of Insulin Receptor (pTyr1162/1163).
Inmunógeno
Human
a synthetic phosphopeptide corresponding to amino acids surrounding the Tyr1162/1163 phosphorylation sites of human insulin receptor
Aplicación
ELISA (see comments)
Immunoblotting (1:1000)
Immunocytochemistry (see comments)
Immunoblotting (1:1000)
Immunocytochemistry (see comments)
Nota de preparación
Following initial thaw, aliquot and freeze (-20°C).
Otras notas
Bevan, P. 2001. J. Cell Sci.114, 1429.
Ottensmeyer, F.P., et al. 2000. Biochemistry39, 12103.
Virkamaki, A., et al. 1999. J. Clin. Invest.103, 931.
Schmid, E., at al. 1998. FASEB J.12, 863.
Hari, J. and Roth, R.A. 1987. J. Biol. Chem.262, 15341.
Morgan, D.O., et al. 1986. Proc. Natl. Acad. Sci. USA83, 328.
White, M.F. and Kahn, C.R. 1986. The Enzymes17, 247.
Ebina, Y., et al. 1985. Cell40, 747.
Ganguly, S., et al. 1985. Current Topics in Cellular Regulation27, 83.
Grunberger, G., et al. 1984. Science223, 932.
Ottensmeyer, F.P., et al. 2000. Biochemistry39, 12103.
Virkamaki, A., et al. 1999. J. Clin. Invest.103, 931.
Schmid, E., at al. 1998. FASEB J.12, 863.
Hari, J. and Roth, R.A. 1987. J. Biol. Chem.262, 15341.
Morgan, D.O., et al. 1986. Proc. Natl. Acad. Sci. USA83, 328.
White, M.F. and Kahn, C.R. 1986. The Enzymes17, 247.
Ebina, Y., et al. 1985. Cell40, 747.
Ganguly, S., et al. 1985. Current Topics in Cellular Regulation27, 83.
Grunberger, G., et al. 1984. Science223, 932.
The immunogen sequence is 100% conserved in the mouse and rat insulin recptor protein, but cross-reactivity has not been tested. This antibody has also been reported to work for ELISA and immunocytochemistry. Variables associated with assay conditions will dictate the proper working dilution.
Información legal
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Cláusula de descargo de responsabilidad
Toxicity: Standard Handling (A)
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Código de clase de almacenamiento
10 - Combustible liquids
Clase de riesgo para el agua (WGK)
WGK 1
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
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