D6750

Sigma-Aldrich

Sodium deoxycholate

≥97% (titration)

Sinónimos:
Desoxycholic acid sodium salt, 3α,12α-Dihydroxy-5β-cholanic acid sodium salt, 7-Deoxycholic acid sodium salt
Empirical Formula (Hill Notation):
C24H39NaO4
Número de CAS:
Peso molecular:
414.55
Beilstein/REAXYS Number:
3581950
Número de EC:
Número MDL:
ID de la sustancia en PubChem:
NACRES:
NA.21

origen biológico

bovine bile

Nivel de calidad

200

descripción

anionic

ensayo

≥97% (titration)

formulario

powder

mol peso

micellar avg mol wt 1200-5000

número de agregación

3-12

CMC

2-6 mM (20-25°C)

HLB

16

grupo funcional

carboxylic acid

enviado en

ambient

temp. de almacenamiento

room temp

SMILES string

[Na+].[H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@H]([C@H](C)CCC([O-])=O)[C@@]4(C)[C@@H](O)C[C@]3([H])[C@@]1(C)CC[C@@H](O)C2

InChI

1S/C24H40O4.Na/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3;/h14-21,25-26H,4-13H2,1-3H3,(H,27,28);/q;+1/p-1/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-;/m1./s1

InChI key

FHHPUSMSKHSNKW-SMOYURAASA-M

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Categorías relacionadas

Descripción general

Sodium deoxycholate is a bile salt and an ionic detergent. Bile salts work along with lipids/fats/cholesterol and form mixed micelles in the intestine. These micelles help in fat digestion and absorption through the intestinal wall.

Aplicación

Sodium deoxycholate has been used in the lysis buffer prepared for brown adipose tissue. It has been used in the decellularization of aortic valvular conduit.

Envase

10, 25, 100, 500 g in poly bottle

Acciones bioquímicas o fisiológicas

Solubilizes fats for absorption in the intestines.

pictogramas

Exclamation mark

Palabra de señalización

Warning

Frases de peligro

hazcat

Acute Tox. 4 Oral

storage_class_code

13 - Non Combustible Solids

WGK Alemania

WGK 1

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Equipo de protección personal

dust mask type N95 (US), Eyeshields, Gloves

Certificado de Análisis

Certificado de origen

Chemistry and biology of bile acids.
Mukhopadhyay S and Maitra U
Current Science, 87, 1666-1683 (2004)
Development of decellularized aortic valvular conduit coated by heparin-SDF-1a multilayer.
Zhou J et al.
The Annals of Thoracic Surgery, 99, 612-612 (2015)
Methods in Cell Biology (1974)
L L Liu et al.
Oncogene, 33(24), 3140-3150 (2013-07-16)
Prostate tumors develop resistance to androgen deprivation therapy (ADT) by multiple mechanisms, one of which is to express constitutively active androgen receptor (AR) splice variants lacking the ligand-binding domain. AR splice variant 7 (AR-V7, also termed AR3) is the most...
Shin Yoshimoto et al.
Nature, 499(7456), 97-101 (2013-06-28)
Obesity has become more prevalent in most developed countries over the past few decades, and is increasingly recognized as a major risk factor for several common types of cancer. As the worldwide obesity epidemic has shown no signs of abating...
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