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Merck

31170

2-Deoxy-D-ribose

≥99.0% (TLC)

Sinónimos:

2-Deoxy-D-arabinose, 2-Deoxy-D-erythropentose, Thyminose

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Fórmula empírica (notación de Hill):
C5H10O4
Número CAS:
533-67-5
Peso molecular:
134.13
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
57648512
EC Number:
208-573-0
Beilstein/REAXYS Number:
1721978
MDL number:
MFCD00135904

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Nombre del producto

2-Deoxy-D-ribose, ≥99.0% (TLC)

InChI key

ASJSAQIRZKANQN-CRCLSJGQSA-N

InChI

1S/C5H10O4/c6-2-1-4(8)5(9)3-7/h2,4-5,7-9H,1,3H2/t4-,5+/m0/s1

SMILES string

OC[C@@H](O)[C@@H](O)CC=O

assay

≥99.0% (TLC)

form

solid

optical activity

[α]20/D −56±2°, 24 hr, c = 1% in H2O

impurities

<0.5% Sulphated ash

ign. residue

≤0.5% (as SO4)

loss

≤1% loss on drying, 20 °C (HV)

color

white

mp

89-90 °C (lit.)

solubility

water: 50 mg/mL, clear, colorless to faintly yellow

storage temp.

2-8°C

Quality Level

200

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1 of 4

Este artículo
121649D589975617
2-Deoxy-D-ribose &#8805;99.0% (TLC)

Sigma-Aldrich

31170

2-Deoxy-D-ribose

2-Deoxy-D-ribose 97% (GC)

Sigma-Aldrich

121649

2-Deoxy-D-ribose

2-Deoxy-D-ribose BioReagent, suitable for cell culture

Sigma-Aldrich

D5899

2-Deoxy-D-ribose

2-Deoxy-L-ribose &#8805;97.0% (TLC)

Sigma-Aldrich

75617

2-Deoxy-L-ribose

assay

≥99.0% (TLC)

assay

97% (GC)

assay

≥99% (GC)

assay

≥97.0% (TLC)

Quality Level

200

Quality Level

100

Quality Level

200

Quality Level

100

solubility

water: 50 mg/mL, clear, colorless to faintly yellow

solubility

-

solubility

water: 100 mg/mL, clear to slightly hazy, colorless to light yellow

solubility

-

form

solid

form

powder

form

powder

form

powder

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

storage temp.

2-8°C

impurities

<0.5% Sulphated ash

impurities

-

impurities

-

impurities

-

Application

2-Deoxy-D-ribose is used to study processes of oxidative stress and glycation in vivo and in vitro. 2-Deoxy-D-ribose, an endothelial-cell chemoattractant and angiogenesis-inducing factor, is used to study processes of tumor angiogenesis and progression mediated at the level of thymidine phosphorylase activity.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
BCCN2641
BCBZ3409
BCBV4136
BCBT0202
BCBQ6795V

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N S Brown et al.
The Biochemical journal, 334 ( Pt 1), 1-8 (1998-08-07)
Angiogenesis is the term used to describe the formation of new blood vessels from the existing vasculature. In order to attract new vessels, a tissue must release an endothelial-cell chemoattractant. 2-Deoxy-D-ribose is produced in vivo by the catalytic action of
Guillaume Mata et al.
The Journal of organic chemistry, 77(20), 9006-9017 (2012-09-15)
An efficient method for the N-2-deoxyribosylation of modified nucleobases by 2-deoxythioriboside donors is reported. In the presence of an in situ silylated nucleobase, thioglycosides can be activated with NIS/HOTf to give nucleosides in high yields and with good β-selectivity. By
Kazumi Taniho et al.
Bioorganic & medicinal chemistry letters, 22(7), 2518-2521 (2012-03-02)
To elucidate the role of the sugar moiety in the two natural nucleotides of the 3'-overhang region of small interfering RNA (siRNA), we synthesized siRNAs that incorporated two abasic nucleosides, 1-deoxy-D-ribofuranose (R(H)). We improved the method for preparing an O-protected
Katarzyna Lamparska et al.
Nucleic acids research, 40(19), 9788-9801 (2012-08-02)
5-Aza-2'-deoxycytidine (5azaC-dR) has been employed as an inhibitor of DNA methylation, a chemotherapeutic agent, a clastogen, a mutagen, an inducer of fragile sites and a carcinogen. However, its effects are difficult to quantify because it rapidly breaks down in aqueous
Anita R Peoples et al.
Nucleic acids research, 40(13), 6060-6069 (2012-04-03)
Our mechanistic understanding of damage formation in DNA by the direct effect relies heavily on what is known of free radical intermediates studied by EPR spectroscopy. Bridging this information to stable product formation requires methods with comparable sensitivities, a criterion
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