C223

Cirazoline hydrochloride

solid

• Sinónimos: 2-[(2-Cyclopropylphenoxy)methyl]-4,5-dihydro-1H-imidazole hydrochloride
• Fórmula empírica (notación de Hill): C₁₃H₁₆N₂O · HCl
• Número CAS: 40600-13-3
• Peso molecular: 252.74
• NACRES: NA.77
• PubChem Substance ID: 24277770
• UNSPSC Code: 12352200
• EC Number: 254-995-3
• MDL number: MFCD00274034
• Form: solid

Propiedades

• form: solid
• Quality Segment: 100
• color: white
• solubility: H₂O: >35 mg/mL
• SMILES string: Cl[H].C1CN=C(COc2ccccc2C3CC3)N1
• InChI: 1S/C13H16N2O.ClH/c1-2-4-12(11(3-1)10-5-6-10)16-9-13-14-7-8-15-13;/h1-4,10H,5-9H2,(H,14,15);1H
• InChI key: XFRXWLWUUDJHPB-UHFFFAOYSA-N
• Gene Information: human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)

Descripción

Application

Cirazoline hydrochloride has been used to activate the α1-noradrenergic receptors and to study the inhibitory effect of neurokinin1 (NK1) antagonists on respiratory activity using the brainstem transverse slice.

Biochem/physiol Actions

Cirazoline is a selective α1-adrenoceptor agonist and also a non-selective ligand for the imidazoline binding site. Cirazoline dereases spatial working memory performance in aged monkeys.

Features and Benefits

This compound is featured on the α1-Adrenoceptors and Imidazoline Binding Sites pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• ¿Qué está pasando?: WGK 3
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable
• EPI (equipos de protección individual): Eyeshields, Gloves, type N95 (US)