This product is a further purification of product H3506 and may contain some residual salts, such as sodium chloride.
H3631
Hialuronidasa from bovine testes
Type VI-S, lyophilized powder, 3,000-15,000 units/mg solid
Sinónimos:
Hialuronato 4-glucanohidrolasa, Hialuronoglucosaminidasa
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Número CAS:
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
253-464-3
MDL number:
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Permítanos ayudarleNombre del producto
Hialuronidasa from bovine testes, Type VI-S, lyophilized powder, 3,000-15,000 units/mg solid
biological source
bovine testis
conjugate
conjugate (Glucosaminoglycan)
type
Type VI-S
form
lyophilized powder
specific activity
3,000-15,000 units/mg solid
mol wt
~55 kDa (four subunits of 14 kDa each)
relevant disease(s)
cancer
storage temp.
−20°C
Quality Level
Gene Information
cow ... HYAL1(515397), HYAL2(281838)
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Categorías relacionadas
Biochem/physiol Actions
Estas enzimas rompen aleatoriamente los enlaces glucosídicos β-N-acetilhexosamina [1→4] del ácido hialurónico, la condroitina y los sulfatos de condroitina.
La hialuronidasa degrada el hialuronano y se ha observado que su regulación no es apropiada durante la progresión del cáncer.
Other Notes
View more information on enzymes for complex carbohydrate analysis at www.sigma-aldrich.com/enzymeexplorer
One unit will degrade 0.75 μg of the polysaccharide hyaluronic acid per minute at pH 5.35 at 37 ºC (as measured by turbidimetric absorbance (λ: 600nm) when complexed with BSA after 45 minutes).
Preparation Note
Chromatographically purified
signalword
Danger
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Dong-Ru Ho et al.
International journal of urology : official journal of the Japanese Urological Association, 18(7), 525-531 (2011-05-25)
To investigate how hyaluronic acid (HA) affects nerve growth factor (NGF) production and bladder overactivity in a cyclophosphamide (CYP)-induced cystitis rat model. Female Sprague-Dawley rats received three intermittent intraperitoneal injections of CYP (75 mg/kg) or saline. Before or after CYP injection
Tongcui Ma et al.
eLife, 11 (2022-07-06)
High-parameter single-cell phenotyping has enabled in-depth classification and interrogation of immune cells, but to date has not allowed for glycan characterization. Here, we develop CyTOF-Lec as an approach to simultaneously characterize many protein and glycan features of human immune cells
Tongcui Ma et al.
eLife, 9 (2020-05-27)
The female reproductive tract (FRT) is the most common site of infection during HIV transmission to women, but viral remodeling complicates characterization of cells targeted for infection. Here, we report extensive phenotypic analyses of HIV-infected endometrial cells by CyTOF, and
Shared decision making, thrombotic thrombocytopenic purpura, and caplacizumab.
Senthil Sukumar et al.
American journal of hematology, 95(4), E76-E77 (2020-01-03)
Nathan V Welham et al.
Journal of speech, language, and hearing research : JSLHR, 52(4), 1008-1020 (2009-07-31)
To develop and evaluate a rat excised larynx model for the measurement of acoustic, aerodynamic, and vocal fold vibratory changes resulting from vocal fold scar. Twenty-four 4-month-old male Sprague-Dawley rats were assigned to 1 of 4 experimental groups: chronic vocal
Artículos
Explore the role of hyaluronan, hyaluronic acid structure, hyaluronan synthesis & degradation, and more. Find GAGs, hydrogels, and scaffold kits.
Uncover more about glycosaminoglycans and proteoglycans including the structure of glycosaminoglycans (GAGs), the different types of GAGs, and their functions.
Glycosaminoglycans are large linear polysaccharides constructed of repeating disaccharide units.
Protocolos
To measure hyaluronidase activity, a turbidimetric determination assay is used at 600 nm. One unit of hyaluronidase activity will cause a change in absorbance of 0.330 per minute at pH 5.35 at 37 °C.
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We bought this product. H3631, Batch Number: SLCH2685. Could you please provide the info on componants like, what are other componants present along with Hyaluronidase which is 3909/mg of solid (40ug, what is the remaining 940ug)?
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