I2393

IL-1β rat

≥98% (SDS-PAGE and HPLC), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

• Sinónimos: IL-1β, Interleukin-1β from rat, Lymphocyte activating factor
• Número MDL: MFCD01094098
• Código UNSPSC: 12352202
• NACRES: NA.77

Propiedades

• Nombre del producto: Interleukin-1β from rat, IL-1β, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
• origen biológico: rat
• Nivel de calidad: 100
• recombinante: expressed in E. coli
• Ensayo: ≥98% (SDS-PAGE and HPLC)
• Formulario: lyophilized powder
• potencia: 0.01-0.1 ng/mL ED₅₀/EC₅₀
• mol peso: 17.3 kDa
• envase: pkg of 10 and 50 μg
• técnicas: cell culture | mammalian: suitable
• impurezas: <0.1 EU/μg
• Nº de acceso UniProt: Q63264
• temp. de almacenamiento: −20°C
• Información sobre el gen: rat ... Il1b(24494)

Descripción

Descripción general

Interleukin-1 (IL-1), originally known as Lymphocyte Activating Factor (LAF), activates T cells and lymphocytes, which then proliferate and secrete interleukin-2.¹ IL-1 is primarily released from stimulated macrophages and monocytes, but is also released from several other cell types,² and is thought to play a key role in inflammatory and immune responses.³ Other synonyms for IL-1 include: Endogenous Pyrogen (EP), Mitogenic Protein (MP), Helper Peak-1 (HP-1), T Cell Replacing Factor III (TRF III or TRF_H), B cell Activating Factor (BAF) and B Cell Differentiation Factor (BDF).⁴ The two closely related agents, Interleukin-1α (IL-1α) and Interleukin-1β (IL-1β) bind to the same cell surface receptor, elicit nearly identical biological responses and yet share 25% homology in their amino acid sequence. Recombinant rat IL-1β is a 17.3 kDa protein containing 153 amino acid residues.

Forma física

Lyophilized from a 0.2 μm filtered buffered solution.

Nota de análisis

The biological activity is measured in a cell proliferation assay using murine D10S cells.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)