SRP4134

IL-3 human

recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)

• Sinónimos: HCGF, IL-3, Interleukin-3, MCGF (Mast cell growth factor), MGC79398, Multi-CSF, P-cell stimulation factor
• Número MDL: MFCD00147276
• Código UNSPSC: 12352202
• NACRES: NA.32

Propiedades

• origen biológico: human
• recombinante: expressed in E. coli
• Ensayo: ≥98% (HPLC); ≥98% (SDS-PAGE)
• Formulario: lyophilized
• mol peso: ~15.0 kDa
• envase: pkg of 10 μg
• impurezas: endotoxin, tested
• Nº de acceso NCBI: P08700
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• Información sobre el gen: human ... IL3(3562)

Descripción

Descripción general

IL-3 is a species-specific colony-stimulating factor that stimulates colony formation of megakaryocytes, neutrophils, and macrophages from bone marrow cultures. Recombinant human IL-3 is a 15.0 kDa protein containing 133 amino acid residues.

Acciones bioquímicas o fisiológicas

Interleukin-3 (IL-3) is a hematopoietic growth factor. The gene encoding it is localized on human chromosome 5.[1] It has a role in cell proliferation and activates different signaling cascades. It is crucial for the differentiation of hematopoietic-derived endothelial progenitor cells (EPCs). The differentiation of erythroid cells, mast cells and granulocytes is stimulated by IL-3. The protein has been linked to schizophrenia.[2][3][4][5]

Forma física

Lyophilized without additives.

Nota de preparación

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitute in water to a concentration of 0.1-1.0 mg/mL. The solution can then be diluted into other aqueous buffers.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable