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  • The anti-lipidemic role of soluble dietary fiber extract from okara after fermentation and dynamic high-pressure microfluidization treatment to Kunming mice.

The anti-lipidemic role of soluble dietary fiber extract from okara after fermentation and dynamic high-pressure microfluidization treatment to Kunming mice.

Journal of food science and technology (2020-10-20)
Derong Lin, Jingjing Wu, Yuanmeng Yang, Xiaomei Long, Zhijun Wu, Wen Qin
RESUMEN

The present study was conducted to evaluate the anti-hyperlipidemia ability of the dietary fiber extracted from okara in mice fed a high cholesterol diet. The dietary fiber was extracted from okara by combining fermentation with dynamic high-pressure microfluidization. An animal model was established to test the hypothesis that soluble dietary fiber, insoluble dietary fiber and total dietary fiber inhibit the fatty liver could be related to the total lipids and cholesterol including total cholesterol, triglyceride, low-density lipoprotein cholesterol and high-density lipoprotein cholesterol in the serum. Compared with mice fed with simvastatin, mice fed dietary fiber can significantly reduce their serum total cholesterol, low-density lipoprotein cholesterol, triglyceride, and atherogenic index whereas no significant effect on high-density lipoprotein cholesterol was observed. Dietary fiber lowered a high level of liver total cholesterol and triglyceride. The dietary fiber extracted from okara might play an important role in the prevention of hyperlipidemia in high cholesterol mice and could be used as a natural supplement to a high cholesterol diet of functional food, due to the suppression of liver lipid synthesis.

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Supelco
Amyloglucosidase solution from Aspergillus niger, for use in Total Dietary Fiber Assay, TDF-100A
Sigma-Aldrich
α-Amylase, heat-stable, solution, for use in Total Dietary Fiber Assay, TDF-100A
Sigma-Aldrich
Protease from Bacillus licheniformis, lyophilized powder, for use in Total Dietary Fiber Assay, TDF-100A