Dissolution of gall-stones in vitro.

Journal of the Indian Medical Association (1991-05-01)
R P Modi, T C Jain, J C Baid, M Maheshwari

An in vitro study on dissolution of 36 gall-stones obtained from 3 patients (12 stones from each patient) was carried out in heparin, bile salt and clofibrate solutions of different strengths. Heparin was found to be a poor solvent while bile salt (sodium desoxycholate) proved better and clofibrate the best solvent in various concentrations used. In addition 3 stones, one from each patient, were placed in normal saline to serve as control.

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Sodium deoxycholate monohydrate, BioXtra, ≥99.0% (titration)