578045

4-Morpholinopiperidine

98%

• Synonym(s): 4-(4-Piperidinyl) morpholine
• Empirical Formula (Hill Notation): C₉H₁₈N₂O
• CAS Number: 53617-35-9
• Molecular Weight: 170.25
• MDL number: MFCD03274733
• UNSPSC Code: 12352100
• PubChem Substance ID: 24880906
• NACRES: NA.22

Properties

• Assay: 98%
• bp: 100-115 °C/0.15-0.20 mmHg (lit.)
• mp: 40-43 °C (lit.)
• functional group: ether
• SMILES string: C1CC(CCN1)N2CCOCC2
• InChI: 1S/C9H18N2O/c1-3-10-4-2-9(1)11-5-7-12-8-6-11/h9-10H,1-8H2
• InChI key: YYBXNWIRMJXEQJ-UHFFFAOYSA-N

Description

Application

4-Morpholinopiperidine may be used to synthesize 2-(4-morpholinopiperidin-1-yl)-5-nitrobenzonitrile[1] and 9-bromo-6,6-dimethyl-8-(4-morpholin-4-yl-piperidin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile.[2]

Reactant for synthesis of:

• Selective adenosine A2A receptor antagonists
• Antidepressents
• Small molecules that restore E-cadherin expression and reduce invasion in colorectal carcinoma cells
• Orally bioavailable P2Y12 antagonists for inhibition of platelet aggregation
• Quinoline derivatives with antimicrobial activity
• Antimalarials

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves