D9175

Dantrolene sodium salt

Ca2+ release from sarcoplasmic reticulum inhibitor, solid

• Synonym(s): 1-[(5-­(p-Nitro­phenyl)­fur­furyl­idene)­amino]­hydan­toin sodium salt
• Empirical Formula (Hill Notation): C₁₄H₉N₄NaO₅
• CAS Number: 14663-23-1
• Molecular Weight: 336.23
• MDL number: MFCD00079130
• UNSPSC Code: 12352200
• PubChem Substance ID: 24278823
• NACRES: NA.77

Properties

• Product Name: Dantrolene sodium salt,
• form: solid
• Quality Level: 200
• originator: JHP Pharmaceuticals
• SMILES string: [Na+].[H]\C(=N/N1CC(=O)N=C1[O-])c2ccc(o2)-c3ccc(cc3)[N+]([O-])=O
• InChI: 1S/C14H10N4O5.Na/c19-13-8-17(14(20)16-13)15-7-11-5-6-12(23-11)9-1-3-10(4-2-9)18(21)22;/h1-7H,8H2,(H,16,19,20);/q;+1/p-1/b15-7+;
• InChI key: KSRLIXGNPXAZHD-HAZZGOGXSA-M
• Gene Information: human ... RYR1(6261), RYR3(6263)

Description

Biochem/physiol Actions

Inhibitor of Ca²⁺ release from sarcoplasmic reticulum; muscle relaxant.

Features and Benefits

This compound is featured on the InsP3/Ryanodine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by JHP Pharmaceuticals. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable