TOX8

In Vitro Toxicology Assay Kit, Resazurin based

Name: <I>In Vitro</I> Toxicology Assay Kit, Resazurin based
Brand: SIGMA
Price: 326 EUR

Synonym(s):

Fluorescent resazurin toxicology assay

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1 KIT

€326.00

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About This Item

EC Number:

263-718-5

UNSPSC Code:

12352207

NACRES:

NA.84

Key Documents

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form

liquid

usage

1 kit sufficient for 2,000 tests

packaging

pkg of 1 kit

storage condition

dry at room temperature

technique(s)

protein quantification: suitable

application(s)

cell analysis
detection

detection method

colorimetric
fluorometric

storage temp.

2-8°C

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This Item	TOX4	TOX7	TOX1
Sigma-Aldrich TOX8 In Vitro Toxicology Assay Kit, Resazurin based	Sigma-Aldrich TOX4 In Vitro Toxicology Assay Kit, Neutral Red based	Sigma-Aldrich TOX7 In Vitro Toxicology Assay Kit, Lactic Dehydrogenase based	Sigma-Aldrich TOX1 In Vitro Toxicology Assay Kit, MTT based
technique(s) protein quantification: suitable	technique(s) -	technique(s) protein quantification: suitable	technique(s) -
form liquid	form liquid	form liquid	form -
usage 1 kit sufficient for 2,000 tests	usage 1 kit sufficient for 1,000 tests	usage kit sufficient for 500 tests	usage 1 kit sufficient for 1,000 tests
packaging pkg of 1 kit	packaging pkg of 1 kit	packaging pkg of 1 kit	packaging pkg of 1 kit
storage condition dry at room temperature	storage condition dry at room temperature	storage condition dry at room temperature	storage condition dry at room temperature
cytotoxicity assay substrate, tetrazolium dye based, fluroescence determination, 600 nM detection	cytotoxicity assay substrate, colorimetric determination, 540 nM detection	cytotoxicity assay substrate, tetrazolium dye based, colorimetric determination, 490 nM detection	cytotoxicity assay substrate, MTT dye based, colorimetric determination, 570 nM detection

General description

In Vitro Toxicology Assay Kit (Resazurin based) is designed for fluorometrically or spectrophotometrically determining cell number as a function of metabolic activity using the dye resazurin. The resazurin method is simple, accurate, and reproducible

Application

In Vitro Toxicology Assay Kit, Resazurin based has been used:

in cell viability assay of human primary fibroblasts[1]
to determine the cell proliferation rate in murine pre-osteoblasts[2]
to determine the metabolic activity of microfluidic and monolayer cultures[3]

Biochem/physiol Actions

Bioreduction of the dye reduces the amount of its oxidized form (blue) and concomitantly increases the fluorescent intermediate (red).

related product

Product No.

Description

Pricing

08168

Timestrip Plus^™ 8 °C

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number

0000497938

0000338679

0000277441

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The dehydrogenase assay with resazurin: practical performance as a monitoring system and Ph-dependent toxicity of phenolic compounds.

U J Strotmann et al.

Ecotoxicology and environmental safety, 25(1), 79-89 (1993-02-01)

The dehydrogenase assay with resazurin as an oxidoreduction dye was used for monitoring the performance of six laboratory-scale sewage treatment plants. The dehydrogenase activity measured proved to be a reliable monitoring parameter, although it did not always positively correlate with

A rapid biochemical test for measuring chemical toxicity.

D Liu

Bulletin of environmental contamination and toxicology, 26(2), 145-149 (1981-02-01)

Comparison of several microbiological toxicity screening tests.

Dutka, B.J., et al.

Water Research, 17, 1363-1367 (1983)

A comparative study of methods for assessing the toxicity to bacteria of single chemicals and mixtures.

King, E.F. et al.

Toxicity Screening Procedures Using Bacterial Systems, 175-194 (1984)

The Influence of Aging on the Regenerative Potential of Human Adipose Derived Mesenchymal Stem Cells.

Monika Marędziak et al.

Stem cells international, 2016, 2152435-2152435 (2016-03-05)

Tissue regeneration using human adipose derived mesenchymal stem cells (hASCs) has significant potential as a novel treatment for many degenerative bone and joint diseases. Previous studies have established that age negatively affects the proliferation status and the osteogenic and chondrogenic

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