8.17073
Fumaric acid
EMPROVE® ESSENTIAL, NF, JPE
Synonym(s):
Fumaric acid, trans-1,2-Ethylentricarboxylic acid
Select a Size
About This Item
Skip To
Agency
JPE
NF
Quality Level
vapor pressure
<0.001 hPa ( 20 °C)
product line
EMPROVE® ESSENTIAL
form
solid
autoignition temp.
375 °C
potency
9300 mg/kg LD50, oral (Rat)
20000 mg/kg LD50, skin (Rabbit)
technique(s)
API processing | cocrystal formation: suitable
API processing | salt formation: suitable
pH
2.1 (20 °C, 4.9 g/L in H2O)
bp
290 °C/1013 hPa (sublimed)
mp
287 °C
transition temp
flash point 273 °C
solubility
4.9 g/L
density
1.64 g/cm3 at 20 °C
application(s)
liquid formulation
pharmaceutical
solid formulation
storage temp.
15-25°C
SMILES string
[O-]C(=O)\C=C\C(=O)[O-].[H+].[H+]
InChI
1S/C4H4O4/c5-3(6)1-2-4(7)8/h1-2H,(H,5,6)(H,7,8)/b2-1+
InChI key
VZCYOOQTPOCHFL-OWOJBTEDSA-N
1 of 4
This Item | F0600000 | PHR1270 | 76635 |
|---|---|---|---|
| application(s) liquid formulation | application(s) pharmaceutical (small molecule) | application(s) pharmaceutical (small molecule) | application(s) cleaning products |
| technique(s) API processing | cocrystal formation: suitable, API processing | salt formation: suitable | technique(s) - | technique(s) HPLC: suitable, gas chromatography (GC): suitable | technique(s) HPLC: suitable, gas chromatography (GC): suitable |
| agency JPE, NF | agency EP Reference Standard | agency traceable to Ph. Eur. F0600000, traceable to USP 1286708 | agency - |
| form solid | form - | form - | form - |
| density 1.64 g/cm3 at 20 °C | density - | density - | density - |
| product line EMPROVE® ESSENTIAL | product line - | product line - | product line - |
General description
As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.
Application
Legal Information
used together
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
523.4 °F
Flash Point(C)
273 °C
Stay compliant with GMP using the Emprove® Program
Accelerate qualification, maintain compliance, and save time with Emprove® Dossiers.
Note: you will be brought to EmproveSuite.com. Your username and password are separate from SigmaAldrich.com and may differ.
Register for free and access Emprove® Dossiers within minutes. Upgrade your subscription plan to unlock advanced and customized content in the Emprove® Suite
Not finding what you are looking for? Visit the Emprove® Program Help page.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Active Filters
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service