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Merck

69732

Lithium mupirocin Supplement

suitable for microbiology,

Selectively inhibits the growth of lactic acid bacteria

Synonym(s):

Lithium mupirocin solution, Li-MUP, MUP supplement

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10 X 5 ML

€264.00

10 X 25 ML

€356.00

€264.00

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About This Item

Empirical Formula (Hill Notation):
C26H43LiO9
CAS Number:
73346-79-9
Molecular Weight:
506.56
MDL number:
MFCD11977847
UNSPSC Code:
41171614
PubChem Substance ID:
329761909
NACRES:
NA.85

Key Documents

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Agency

ISO 29981:2010

Quality Level

100

sterility

sterile (Filtered and Aseptic Handled)
sterile

form

liquid

shelf life

limited shelf life, expiry date on the label

application(s)

environmental
food and beverages
microbiology

storage temp.

2-8°C

suitability

Lactobacillus spp.
Lactococcus spp.
Leuconostoc spp.
Streptococcus spp.

SMILES string

[Li+].C[C@H](O)[C@H](C)[C@@H]1O[C@H]1C[C@H]2CO[C@@H](C\C(C)=C\C(=O)OCCCCCCCCC([O-])=O)[C@H](O)[C@@H]2O

InChI

1S/C26H44O9.Li/c1-16(13-23(30)33-11-9-7-5-4-6-8-10-22(28)29)12-20-25(32)24(31)19(15-34-20)14-21-26(35-21)17(2)18(3)27;/h13,17-21,24-27,31-32H,4-12,14-15H2,1-3H3,(H,28,29);/q;+1/p-1/b16-13+;/t17-,18-,19-,20-,21-,24+,25-,26-;/m0./s1

InChI key

XFIKMPRBSORKQP-JATHGWPISA-M

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This Item
PHR3421M38060001448923
Lithium mupirocin Supplement suitable for microbiology, Selectively inhibits the growth of lactic acid bacteria

Millipore

69732

Lithium mupirocin Supplement

Mupirocin Lithium certified reference material, pharmaceutical secondary standard

Supelco

PHR3421

Mupirocin Lithium

Mupirocin lithium European Pharmacopoeia (EP) Reference Standard

M3806000

Mupirocin lithium

Mupirocin lithium United States Pharmacopeia (USP) Reference Standard

USP

1448923

Mupirocin lithium

suitability

Lactobacillus spp., Leuconostoc spp., Lactococcus spp., Streptococcus spp.

suitability

-

suitability

-

suitability

-

application(s)

environmental
food and beverages, microbiology

application(s)

pharmaceutical

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

form

liquid

form

-

form

-

form

-

sterility

sterile (Filtered and Aseptic Handled)

sterility

-

sterility

-

sterility

-

storage temp.

2-8°C

storage temp.

-10 to -25°C

storage temp.

2-8°C

storage temp.

-

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

-

shelf life

-

General description

Lithium mupirocin is isolated from Pseudomonas fluorescens. At lower concentrations, it has bacteriostatic characteristics, while at higher concentrations it is bacteriocidal. Mupirocin is active against gram-positive bacteria such as Methicillin-resistant Staphylococcus aureus (MRSA), Lactobacilli, Lactococci, Streptococci and Leuconostocs. Mupirocin has been used to study mupirocin resistance in Mycoplasma bacteria. Mupirocin inhibits the isoleucyl-tRNA synthetase, which finally results in inhibition of protein and RNA synthesis. Mupirocin lithium salt is freely soluble in water.

Application

Lithium mupirocin supplement is used for selective enumeration of Bifidobacteria from fermented milk products along with the TOS-propionate agar according to ISO 29981:2010 and IDF 220:2010

Other Notes

Composition:
(5ml, sufficient for 100 ml medium)
Mupirocin 5 mg
sterile distilled water 5.0 ml

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM4587
BCCJ9097
BCCH6039
BCCH0638
BCCG6315

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Variation, viability and validity of bifidobacteria in fermented milk products.
Raeisi, Shahram Naghizadeh, et al.
Food Control, 34, 691-697 (2013)
J Gilbart et al.
Antimicrobial agents and chemotherapy, 37(1), 32-38 (1993-01-01)
Mupirocin resistance in Staphylococcus aureus results from changes in the target enzyme, isoleucyl-tRNA synthetase (IRS). Twelve strains of S. aureus comprising four susceptible (MICs < or = 4 micrograms/ml), four intermediate level-resistant (MICs between 8 and 256 micrograms/ml), and four
Krešimir Matanovic et al.
Journal of clinical microbiology, 51(3), 1005-1007 (2012-12-28)
The genetic analysis of high-level mupirocin resistance (Hi-Mup(r)) in a Staphylococcus pseudintermedius isolate from a dog is presented. The Hi-Mup(r) ileS2 gene flanked by a novel rearrangement of directly repeated insertion sequence IS257 elements was located, together with the aminoglycoside
Staph aureus has long been recognized as being more prevalent in cultures from patients with chronic rhinosinusitis(CRS) compared to those with acute rhinosinusitis.
Peter H Hwang
International forum of allergy & rhinology, 3(2), 81-82 (2013-02-16)
Kristin A Seiberling et al.
International forum of allergy & rhinology, 3(2), 94-98 (2012-11-30)
Antibiotic irrigations are occasionally used during endoscopic sinus surgery when gross mucosal infection is present. These irrigations are thought to flush out pathogenic bacteria and decrease the bacterial load within the mucosal surfaces. This treatment, however, has not been studied
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